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Clinical Trial Registration: The Time Has Come
Leighton Chan1, Allen W Heinemann1
1Leighton Chan, MD, MPH, and Allen W. Heinemann, PhD, are Co-Editors-in-Chief, Archives of Physical Medicine and Rehabilitation.
Summary
The American Journal of Occupational Therapy (AJOT) now requires clinical trial registration for all submitted manuscripts. This policy enhances research integrity by documenting study designs and primary outcomes.
Area of Science:
- Rehabilitation Medicine
- Clinical Research Ethics
Background:
- AJOT mandates clinical trial registration for all submitted manuscripts.
- This collaborative initiative with other major rehabilitation and disability journals aims to improve research transparency.
Discussion:
- Authors must register clinical trials before manuscript submission.
- Retrospective registration is permitted for ongoing trials enrolling patients.
- Multiyear studies ongoing before January 1, 2017, may be published with special permission.
Key Insights:
- Clinical trial registration enhances the quality and integrity of published research.
- The policy ensures documentation of original study designs and primary outcome measures.
- Interim measures facilitate author education on trial registration importance.
Outlook:
- This policy is expected to elevate the overall quality of articles published in AJOT.
- Mandatory registration aligns AJOT with evolving standards in scientific publishing.
- Future publications will benefit from increased data reliability and reproducibility.
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