Related Experiment Video
Updated: Mar 28, 2026
How to Administer Near-Infrared Spectroscopy in Critically ill Neonates, Infants, and Children
Published on: August 19, 2020
Haemoglobin Levels in Acute Coronary Syndrome Patients Admitted in Cardiology Intensive Care Units in a Tertiary Care
Insights
This study found that while mean hemoglobin levels decreased with increasing coronary artery disease severity in Indian patients, anemia was not statistically linked to more severe coronary artery disease. Further research is needed to clarify this relationship.
Area of Science:
- Cardiology
- Hematology
- Epidemiology
Background:
- Abnormal hemoglobin levels and their link to coronary artery disease (CAD) severity in Indian patients remain unclear.
- Acute coronary syndrome (ACS) is a significant health concern, and understanding associated factors like hemoglobin levels is crucial.
Purpose of the Study:
- To investigate hemoglobin levels in patients experiencing acute coronary syndrome (ACS).
- To determine the association between anemia and the severity of coronary artery disease (CAD) as assessed by coronary angiography (CAG).
Main Methods:
- Prospective observational study enrolling 162 patients diagnosed with ACS.
- Recorded baseline hemoglobin levels and assessed CAD severity using coronary angiography (CAG) in 101 patients.
Main Results:
- 62.96% of patients had anemia; abnormal high hemoglobin was exclusive to males.
- Anemia was present in 58.82% of patients who underwent CAG.
- Mean hemoglobin levels decreased with increasing CAD severity in anemic patients, but the overall association between anemia and CAD severity was not statistically significant.
Conclusions:
- Hemoglobin levels tend to decrease as coronary artery disease (CAD) severity increases.
- A statistically significant association between anemia and the severity of coronary artery disease (CAD) was not established in this cohort.
Objective:
Epidemiology of abnormal haemoglobin levels and its association with severity of coronary artery disease in Indian patients is uncertain. This prospective observational study was conducted to determine the haemoglobin levels in acute coronary syndrome (ACS) patients and the association of anaemia with the severity of coronary artery disease (CAD) on coronary angiography (CAG).
Methods:
The patients diagnosed with ACS (ST-elevated and non-elevated MI, unstable angina) based on ECG and cardiac enzymes and admitted in cardiology ICU were enrolled in the study after fulfilling study criteria and the baseline haemoglobin level was recorded. The severity of coronary disease of patients who underwent coronary angiography was recorded.
Results:
A total of 162 patients were enrolled for the study. The overall haemoglobin of patients was 11.99 ± 2.24 g/dl with 12.46 ± 2.33 g/dl in males and 11.17 ± 1.82 g/dl in females (p < 0.05). Anaemia was found in 62.96% patients with no significant gender difference (p > 0.05), however abnormal haemoglobin level (Hb > 16g/dl) was found exclusively in 7.7% males. One hundred one patients underwent coronary angiography and anaemia was present in 60 patients (58.82%) and absent in 41 (40.59%). The difference in mean haemoglobin levels in anaemic patients with single, double, and triple vessel disease was significant (p < 0.05) and corresponding levels in non-anaemic patients were insignificant (p > 0.05). A weak correlation was observed between the haemoglobin level of patients and the percentage of obstruction in CAG (r = 0.26). The odds of having triple vessel disease in anaemic patient are 1.77 (95% CI 0.71 to 4.43). However, the association between anaemia and the severity of coronary artery disease was statistically found to be non-significant.
Conclusion:
The mean haemoglobin levels decreased as the severity of CAD increased in CAG, however the association was not established between anaemia and the severity of coronary artery disease statistically.
More Related Videos
Related Concept Videos
01:30Acute Coronary Syndrome III: Diagnostic Studies
01:20Blood Studies for Cardiovascular System I: Cardiac Biomarkers
The essential diagnostic tools for detecting myocardial necrosis and monitoring individuals suspected of having acute coronary syndrome (ACS) include:
Troponins
Troponins, particularly cardiac troponins I and T, are the most precise and sensitive markers of myocardial injury. They are detectable within 4-6 hours of myocardial injury and remain...
01:30Acute Coronary Syndrome I: Introduction
01:28Acute Coronary Syndrome IV: Interprofessional Care
01:26Acute Coronary Syndrome V: Nursing Management
01:19Acute Coronary Syndrome II: Pathophysiology and Clinical Manifestations