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Preoperative ManagementThe primary goals of preoperative management in kidney transplantation are to optimize the patient’s metabolic state and prepare them for surgery through diet adjustments, necessary dialysis, and tailored medical treatment. This phase also involves comprehensive infection screening and patient education about the surgical procedure and postoperative care to improve outcomes and adherence.Medical ManagementA comprehensive evaluation is required for both the living...
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Tissue transplantation is a significant medical procedure involving the transfer of cells, tissues, or organs from a donor to a recipient, with the primary aim of restoring lost functions. This procedure is crucial in treating a broad spectrum of diseases, including kidney diseases, liver failure, heart disease, and certain types of cancers.
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Measurement of Two-Point Energy Correlators within Jets in p+p Collisions at sqrt[s]=200  GeV.

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Erratum: Measurement of the Sixth-Order Cumulant of Net-Proton Multiplicity Distributions in Au+Au Collisions at sqrt[s_{NN}]=27, 54.4, and 200 GeV at RHIC [Phys. Rev. Lett. 127, 262301 (2021)].

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Related Experiment Video

Updated: Mar 28, 2026

A Mouse Model of Vascularized Heterotopic Spleen Transplantation for Studying Spleen Cell Biology and Transplant Immunity
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[Hyposlenism After Splenectomy].

D A Morozov, S A Klyuev

    Vestnik Rossiiskoi Akademii Meditsinskikh Nauk
    |December 30, 2015
    PubMed
    Summary

    Splenectomy, the removal of the spleen, can lead to hyposplenism and increased risk of overwhelming postsplenectomy infection. This review highlights the need for diagnostic criteria and prevention strategies for pediatric hyposplenism.

    Area of Science:

    • Immunology
    • Pediatric Surgery

    Context:

    • Splenectomy, removal of the spleen, eliminates a major peripheral immune organ.
    • Hyposplenism diagnosis and postsplenectomy sepsis incidence lack defined criteria and data in Russia.
    • Pediatric splenectomy necessitates clear guidelines for management and prevention.

    Purpose:

    • To review current literature on hyposplenism following splenectomy.
    • To discuss the systemic effects of spleen removal.
    • To outline strategies for preventing overwhelming postsplenectomy infection and sepsis.

    Summary:

    • Splenectomy results in the loss of immune cells and factors, potentially leading to hyposplenism.
    • The review covers changes in the body post-splenectomy and the systemic impact of the operation.

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  • Prevention of postsplenectomy infections and sepsis is a key focus.

    • Impact:

    • Addresses the critical knowledge gap regarding pediatric hyposplenism in Russia.
    • Provides a foundation for developing diagnostic and preventive protocols.
    • Aims to improve patient outcomes by mitigating risks associated with splenectomy.