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Updated: Mar 28, 2026

In Vivo, Percutaneous, Needle Based, Optical Coherence Tomography of Renal Masses
Published on: March 30, 2015
[Computed tomography features and pathological correlations of primitive neuroectodermal tumor of the kidney]
Songwei Yue1, Jingjing Xing, Jianbo Gao2
1Department of Radiology, Department of Pathology, First Affiliated Hospital, Zhengzhou University, Zhengzhou 450052, China.
Objective:
To explore the computed tomography (CT) features and pathological correlations of primitive neuroectodermal tumor (PNET) of the kidney.
Methods:
The CT features of 5 cases of pathologically confirmed PNETs were retrospectively reviewed along with a literature review to analyze the CT features and pathological correlations.
Results:
The age range was 19-78 years. CT image showed solitary mass of heterogeneous density with ill-defined margins. One case had multifocal necrosis. Among 3 cases of cystic changes, there were mural nodule (n = 2) and patchy calcification (n = 1). Four cases showed invasive growth into renal cortex and pelvis with cortical interruption (n = 3) and destruction of renal capsule and invasion into perirenal fat space (n = 1). The tumors were confined to kidney contour with enlarged kidney (n = 3). All 5 cases showed slight heterogenous enhancement in cortico-medullary phase with persistent moderate enhancement (n = 4) and persistent mild enhancement (n = 1) in nephrographic phase.
Conclusion:
Renal PNET is common in young patients with a high degree of malignancy. CT features include large mass with heterogenous density and poor-defined border confined within renal contour. Necrosis and cystic changes occur commonly with invasive growth. Persistent enhancement is found during nephrographic phase. A definite diagnosis is dependent upon pathological and immunohistochemical examinations.
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