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Complete excision of large invasive retroperitoneal paraganglioma mislabelled as hypertrophic obstructive
Tasnim Ahsan1, Amir Latif2, Sara Sohail3
1Department of Medicine, Jinnah Post Graduate Medical Centre, Karachi, Pakistan.
JPMA. the Journal of the Pakistan Medical Association
|December 30, 2015
Abstract:
Paraganglioma originates from chromaffin cells of adrenal medulla and autonomic paraganglia, which are derived from the neural crest cells. Paragangliomas are half as common as pheochromocytomas with 69% occurring in head and neck, 22% in abdomen and pelvis and 10% in the thorax. About 70% paragangliomas are sporadic, 30% are hereditary, having identifiable germline mutations of Succinate Dehydrogenase enzyme (SDH).
