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Treatment of infantile subglottic hemangioma with oral propranolol

Cai-Fu Wang1, Ying-Shuo Wang1, Yue-Feng Sun2

  • 1Departments of Pulmonology, Children's Hospital of Zhejiang University School of Medicine, Hangzhou, China.

Pediatrics International : Official Journal of the Japan Pediatric Society
|December 30, 2015
PubMed

Insights

Oral propranolol effectively treats infantile subglottic hemangioma (SH), resolving symptoms rapidly. This study suggests propranolol as a recommended first-line therapy for infants requiring intervention for SH.

Area of Science:

  • Pediatric Otolaryngology
  • Neonatal Medicine
  • Pharmacology

Background:

  • Infantile subglottic hemangioma (SH) presents a significant clinical challenge, potentially causing severe airway obstruction.
  • Current treatment strategies for SH lack consensus and carry risks of adverse effects.

Observation:

  • Four infants diagnosed with subglottic hemangioma were treated with oral propranolol.
  • Clinical monitoring documented the infants' response to the therapeutic intervention.

Findings:

  • Oral propranolol administration led to rapid symptom resolution within two days for all treated infants.
  • Complete recovery was observed in all cases following propranolol treatment for SH.

Implications:

  • Propranolol demonstrates significant efficacy as a treatment for infantile subglottic hemangioma.
  • The findings support the use of propranolol as a first-line therapeutic option for SH requiring intervention.

Keywords:
infantpropranololsubglottic hemangioma

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