Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Receptor-mediated Endocytosis01:20

Receptor-mediated Endocytosis

11.6K
Receptor-mediated endocytosis is when bulk amounts of specific molecules are imported into a cell after binding to cell surface receptors. The molecules bound to these receptors are taken into the cell through inward folding of the cell surface membrane, which is eventually pinched off into a vesicle within the cell. Structural proteins, such as clathrin, coat the budding vesicle.
Clathrin-Mediated Endocytosis of LDL
One well-characterized example of receptor-mediated endocytosis is the...
11.6K
Receptor-mediated Endocytosis01:38

Receptor-mediated Endocytosis

113.4K
Overview
113.4K
Colonisation of Pathogens01:25

Colonisation of Pathogens

18
Pathogen colonization of host tissues is a critical step in the development of infectious diseases. Various pathogenic microorganisms, including bacteria, fungi, viruses, and protozoa, have evolved complex strategies to attach to, invade, and persist within host environments. These mechanisms enable pathogens to establish infections, evade immune responses, and resist antimicrobial treatments.Attachment to Host CellsIn bacteria, colonization typically begins with adherence to host epithelial...
18
Defense Against Bacterial Pathogens01:31

Defense Against Bacterial Pathogens

3.4K
The human immune system is a complex network of cells, tissues, and organs that work together to defend the body against bacterial infections. It consists of various immune cells, each playing a specific role in the defense mechanism.
Phagocytes
Phagocytes are the frontline soldiers of the immune system. They include neutrophils and macrophages. Neutrophils are the most abundant type of white blood cell and are quickly mobilized to the site of infection. Macrophages are larger cells that patrol...
3.4K
Intracellular Movement of Viruses and Bacteria01:10

Intracellular Movement of Viruses and Bacteria

3.8K
Intracellular bacteria and viruses often comprise a group of highly infectious pathogens that can cause several diseases. Bacterial pathogens include those belonging to the genus Rickettsia responsible for conditions such as rocky mountain spotted fever and the Mediterranean spotted fever; Chlamydia, a genus responsible for a sexually transmitted disease; Coxiella burnetii, an agent responsible for Q fever. Viral pathogens include vaccinia—a poxvirus, and herpes simplex virus—a...
3.8K
Infection01:20

Infection

14.2K
When a pathogen enters the body and reproduces, it can cause an infection, damage body cells, and cause illness symptoms that eventually lead to disease. Therefore, its prevention requires breaking the chain of infection.
The chain begins with pathogens: bacteria, viruses, fungi, prions, or parasites such as protozoa helminths. These can be present on the skin as transient or resident flora, or they can be acquired from the environment. Identifying and treating the type of infection and...
14.2K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Dual membrane-spanning anti-sigma 2 controls OMV biogenesis and colonization fitness in <i>Bacteroides thetaiotaomicron</i>.

Journal of bacteriology·2026
Same author

A multivalent capsule vaccine protects against Klebsiella pneumoniae bloodstream infections in healthy and immunocompromised mice.

NPJ vaccines·2025
Same author

Intracellular <i>Acinetobacter baumannii</i> acts as a transient reservoir in lung infection via a "persist and resist" strategy.

Proceedings of the National Academy of Sciences of the United States of America·2025
Same author

Differential virulence and immune recognition of <i>Klebsiella pneumoniae</i> O-antigen subtypes O2α and O2β.

Infection and immunity·2025
Same author

Glycoengineering the Pseudomonas exotoxin A for multi-sequon integration and enhanced bioconjugation efficiency by PglS.

Glycobiology·2025
Same author

Enhancing O-linking oligosaccharyltransferase functionality through directed evolution.

The Journal of biological chemistry·2025
Same journal

The bacterial SOS response promotes the expression of the transposase encoded by IS<i>CR</i> mobile genetic elements.

Journal of bacteriology·2026
Same journal

Development of a gene-editing strategy to overcome genetic intractability in <i>Lactobacillus johnsonii</i>.

Journal of bacteriology·2026
Same journal

Bactofilins are essential spatial organizers of peptidoglycan insertion in the Lyme disease spirochete <i>Borrelia burgdorferi</i>.

Journal of bacteriology·2026
Same journal

DNA damage-associated vesicle production in <i>Stenotrophomonas maltophilia</i> is mediated by the maltocin endolysin.

Journal of bacteriology·2026
Same journal

Characterization of <i>Helicobacter pylori</i> aggregation reveals a requirement for both AlpA and AlpB.

Journal of bacteriology·2026
Same journal

Cross-regulation of amino acid synthesis and anaerobic electron transfer by MetR-mediated methionine signaling.

Journal of bacteriology·2026
See all related articles

Related Experiment Video

Updated: Mar 28, 2026

Separation of the Cell Envelope for Gram-negative Bacteria into Inner and Outer Membrane Fractions with Technical Adjustments for Acinetobacter baumannii
10:24

Separation of the Cell Envelope for Gram-negative Bacteria into Inner and Outer Membrane Fractions with Technical Adjustments for Acinetobacter baumannii

Published on: April 10, 2020

14.5K

Pathogenic Acinetobacter: from the Cell Surface to Infinity and Beyond.

Brent S Weber1, Christian M Harding2, Mario F Feldman3

  • 1Department of Biological Sciences, University of Alberta, Edmonton, AB, Canada Department of Molecular Microbiology, Washington University School of Medicine in St. Louis, St. Louis, Missouri, USA.

Journal of Bacteriology
|December 30, 2015
PubMed
Summary
This summary is machine-generated.

Acinetobacter bacteria are dangerous hospital pathogens. This review details surface-level virulence factors like capsule and adhesins, crucial for understanding and combating multidrug-resistant strains.

More Related Videos

Author Spotlight: A Comprehensive Protocol for Acinetobacter Biofilm Quantification, Assessment, and Visualization
07:41

Author Spotlight: A Comprehensive Protocol for Acinetobacter Biofilm Quantification, Assessment, and Visualization

Published on: August 4, 2023

4.6K
Author Spotlight: Advancing Antibiotic Resistance Research Using an Efflux&#45;Deficient Bacterial Strain and a Single&#45;Copy Gene Expression System
05:06

Author Spotlight: Advancing Antibiotic Resistance Research Using an Efflux-Deficient Bacterial Strain and a Single-Copy Gene Expression System

Published on: January 5, 2024

1.2K

Related Experiment Videos

Last Updated: Mar 28, 2026

Separation of the Cell Envelope for Gram-negative Bacteria into Inner and Outer Membrane Fractions with Technical Adjustments for Acinetobacter baumannii
10:24

Separation of the Cell Envelope for Gram-negative Bacteria into Inner and Outer Membrane Fractions with Technical Adjustments for Acinetobacter baumannii

Published on: April 10, 2020

14.5K
Author Spotlight: A Comprehensive Protocol for Acinetobacter Biofilm Quantification, Assessment, and Visualization
07:41

Author Spotlight: A Comprehensive Protocol for Acinetobacter Biofilm Quantification, Assessment, and Visualization

Published on: August 4, 2023

4.6K
Author Spotlight: Advancing Antibiotic Resistance Research Using an Efflux&#45;Deficient Bacterial Strain and a Single&#45;Copy Gene Expression System
05:06

Author Spotlight: Advancing Antibiotic Resistance Research Using an Efflux-Deficient Bacterial Strain and a Single-Copy Gene Expression System

Published on: January 5, 2024

1.2K

Area of Science:

  • Microbiology
  • Infectious Diseases
  • Pathogenesis

Background:

  • Genus Acinetobacter includes opportunistic nosocomial pathogens.
  • Acinetobacter baumannii, A. nosocomialis, and A. pittii are prevalent globally.
  • Multidrug-resistant Acinetobacter strains pose a growing health threat.

Purpose of the Study:

  • To review recently identified bacterial surface virulence factors in Acinetobacter.
  • To enhance understanding of Acinetobacter pathogenesis.
  • To inform new strategies against multidrug-resistant infections.

Main Methods:

  • Literature review focusing on bacterial surface factors.
  • Analysis of capsule, O-linked protein glycosylation, and adhesins.
  • Review of type II and type VI secretion systems.

Main Results:

  • Several bacterial surface factors contribute to Acinetobacter colonization.
  • Capsule, O-linked protein glycosylation, and adhesins are key virulence factors.
  • Type II and type VI secretion systems are present in these strains.

Conclusions:

  • Understanding surface virulence factors is essential for combating Acinetobacter infections.
  • Further research into these factors can guide the development of novel therapeutics.
  • Detailed pathobiology knowledge is needed for effective management of multidrug-resistant Acinetobacter.