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Clarithromycin Culprit of Benign Intracranial Hypertension
Habib Rehman Khan1, Colin Mason2, Riona Mulcahy3
1Department of Medicine and Cardiovascular Science, Nottingham NHS Trust, Nottingham, United Kingdom.
Insights
Benign intracranial hypertension, often seen in obese women, causes increased CSF pressure, headaches, and vision loss. Weight management and optic disc monitoring are key for managing this condition.
Area of Science:
- Neurology
- Ophthalmology
Background:
- Benign intracranial hypertension (BIH) is a neurological disorder characterized by elevated cerebrospinal fluid (CSF) opening pressure without a clear cause.
- It disproportionately affects women of childbearing age, particularly those who are obese.
- Untreated BIH can lead to severe headaches and irreversible vision loss.
Abstract:
Benign intracranial hypertension is characterized with increase in CSF opening pressure with no specific etiology. It is predominantly found in women of child bearing age and particularly in individuals with obesity. Visual disturbances or loss and associated headaches are common and can lead to blindness if left untreated. Diagnosis can be achieved once other causes of visual loss, headaches and high opening pressures are excluded. Management consists of serial optic disc assessments although no specific treatment is available despite recent trials using carbonic anhydrase inhibitors. Diet modification and weight management can help in therapy.
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