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Targeting Notch to overcome radiation resistance

Sanaz Yahyanejad1, Jan Theys1, Marc Vooijs1

  • 1Department of Radiotherapy (MAASTRO)/GROW, School for Developmental Biology and Oncology, Maastricht University, Maastricht, The Netherlands.

Oncotarget
|December 30, 2015
PubMed
Summary

Notch signaling drives cancer radiation resistance, hindering tumor cell elimination. Targeting Notch pathways and using biomarkers can improve radiotherapy effectiveness and patient outcomes.

Keywords:
NotchNotch inhibitorpersonalized treatmentradiotherapytreatment resistance

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