Renalase Levels in Children with Solitary Functioning Kidney
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Updated: Mar 28, 2026

Isolation, Characterization, And High Throughput Extracellular Flux Analysis of Mouse Primary Renal Tubular Epithelial Cells
Published on: June 20, 2018
K Taranta-Janusz1, R Roszkowska, A Wasilewska
1Department of Pediatrics and Nephrology, Medical University of Bialystok, Poland. Correspondence to: Dr Katarzyna Taranta-Janusz, Medical University of Bialystok,Department of Pediatrics and Nephrology, 15-274 Bialystok, Waszyngtona 17, Poland. katarzyna.taranta@wp.pl.
Objective:
To measure serum and urine renalase levels in children with a single kidney, and to compare with a reference group.
Methods:
Participants were: solitary kidney (n=36) and healthy children (n=57). Renalase levels were measured using the immunoenzymatic method.
Results:
Serum and urine renalase levels were significantly lower in patients with a solitary kidney compared to healthy children. Urine renalase/creatinine values were negatively related to serum creatinine and positively related to glomerular filtration rate. Significant correlations between renalase levels and blood pressure were not found.
Conclusion:
Prognostic importance of reduced renalase levels in children with a single kidney can only be quantified by further longitudinal study.
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