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Bacterial liver abscess in children
The Journal of the Singapore Paediatric Society
|January 1, 1989
Summary
This study found that percutaneous transhepatic drainage (PTHD) guided by ultrasonography is a safe and effective treatment for pediatric bacterial liver abscesses, with a low mortality rate.
Area of Science:
- Pediatric Infectious Diseases
- Hepatology
- Interventional Radiology
Background:
- Bacterial liver abscesses in children are a significant clinical challenge.
- Early diagnosis and effective management are crucial for favorable outcomes.
Purpose of the Study:
- To analyze the clinical characteristics, management, and outcomes of pediatric bacterial liver abscesses.
- To evaluate the safety and efficacy of percutaneous transhepatic drainage (PTHD) in treating these cases.
Main Methods:
- Retrospective review of 136 children diagnosed with bacterial liver abscess from November 1987.
- Diagnostic methods included radiography, ultrasonography, PTHD, and radioisotope scanning.
- Treatment strategies encompassed surgical drainage, PTHD, and antibiotic therapy.
Main Results:
- Staphylococcus aureus and Escherichia coli were the most common pathogens identified.
- Percutaneous transhepatic drainage (PTHD) was performed in 15 cases with successful survival.
- Antibiotic therapy alone resulted in a mortality rate of 1.47% and a response rate of 36.3%.
Conclusions:
- Percutaneous transhepatic drainage (PTHD) under ultrasonographic guidance is a safe and effective minimally invasive treatment for pediatric bacterial liver abscess.
- Prompt diagnosis and appropriate management, including drainage, are essential to reduce morbidity and mortality.