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Current status and actual need for pediatric liver transplantation in Southern Vietnam

Tu Cam Nguyen1, Annie Robert2, Phuong Van Ngoc Nguyen3

  • 1Gastroenterology, Children's Hospital 2, Ho Chi Minh City, Vietnam.

Pediatric Transplantation
|December 31, 2015
PubMed

Insights

Pediatric liver transplantation (LT) is crucial for end-stage liver disease in children. However, Vietnam faces significant barriers, including cost and donor shortages, limiting access to this life-saving procedure.

Area of Science:

  • Hepatology
  • Pediatric Surgery
  • Public Health

Background:

  • Liver transplantation (LT) significantly improves outcomes for children with end-stage liver disease.
  • The first pediatric LT in Vietnam occurred in 2004, highlighting the procedure's relative novelty in the region.
  • Children's Hospital 2 in Ho Chi Minh City is the sole pediatric LT center in Southern Vietnam.

Purpose of the Study:

  • To evaluate the current demand for pediatric liver transplantation in Southern Vietnam.
  • To identify barriers hindering the implementation of pediatric LT programs in the region.

Main Methods:

  • A retrospective review of 280 pediatric chronic liver disease patients was conducted.
  • Data were collected from patients followed at Children's Hospital 2 between January 2009 and June 2014.
  • Assessment included eligibility for LT and reasons for transplant limitations.

Main Results:

  • Sixty-seven out of 280 patients met criteria for LT.
  • Only one pediatric LT was performed between 2009 and 2014.
  • Parental consent for LT was obtained in only 28.4% of eligible patients.
  • Key barriers included financial costs, distance, lifelong care needs, and organ donor scarcity.

Conclusions:

  • There is a high unmet need for pediatric liver transplantation in Southern Vietnam.
  • Developing the pediatric LT program requires addressing financial, logistical, and donor-related challenges.
  • Sustained efforts are necessary to improve access to pediatric LT in this developing country.

Keywords:
Southern Vietnambiliary atresiachronic liver diseaseparental consentpediatric liver transplantation

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