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Cardiac Catheterization I: Pre-Procedure Overview01:28

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Interprofessional care for coronary artery disease includes pharmacological therapy and revascularization procedures.Pharmacological therapy for Coronary Artery Disease (CAD) aims to manage symptoms, prevent complications, and improve patient outcomes through various classes of medications:Antiplatelet Agents:Aspirin and Clopidogrel: These medications inhibit platelet aggregation, preventing blood clots, which is crucial for avoiding heart attacks and strokes. Doctors often prescribe these...
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Biomechanical performance of an immature maxillary central incisor after revitalization: a finite element analysis.

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Clinical procedures for revitalization: current knowledge and considerations.

K M Galler1

  • 1Department of Conservative Dentistry and Periodontology, University Hospital Regensburg, Regensburg, Germany. kerstin.galler@ukr.de.

International Endodontic Journal
|December 31, 2015
PubMed
Summary

Regenerative endodontics offers a promising alternative to apexification for immature teeth with pulp necrosis, promoting tissue regeneration and root development. Further research is needed to establish optimal protocols and clarify outcomes for this advanced therapeutic approach.

Keywords:
dental pulp stem cellspulp regenerationregenerative endodonticsrevascularizationrevitalization

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Area of Science:

  • Endodontics
  • Regenerative Medicine
  • Dental Traumatology

Background:

  • Regenerative endodontic procedures (REPs) are emerging as a viable alternative to conventional apexification for immature teeth with pulp necrosis.
  • These treatments aim to restore biological function by promoting the formation of vital tissue within the root canal.

Purpose of the Study:

  • To review the current state of regenerative endodontic therapies.
  • To discuss unresolved questions and provide literature-based recommendations for REPs.

Main Methods:

  • Minimal instrumentation and disinfection of root canal walls.
  • Application of intracanal medicaments and provocation of a blood clot.
  • Capping with calcium silicate materials and ensuring a coronal seal.

Main Results:

  • REPs can lead to resolution of pain, inflammation, and periapical lesions.
  • Successful treatment can result in increased root length, thickness, and strength of dentinal walls.
  • Animal studies suggest repair rather than true regeneration, necessitating further outcome assessment.

Conclusions:

  • Regenerative endodontics holds significant potential for treating immature necrotic teeth.
  • Standardization of protocols, including irrigant and medicament selection, is crucial.
  • Further research is required to define patient selection, informed consent, and long-term outcomes.