Related Experiment Video

Updated: Mar 28, 2026

Isolation and Characterization of Cardiac Mesenchymal Stromal Cells from Endomyocardial Bioptic Samples of Arrhythmogenic Cardiomyopathy Patients
09:16

Isolation and Characterization of Cardiac Mesenchymal Stromal Cells from Endomyocardial Bioptic Samples of Arrhythmogenic Cardiomyopathy Patients

Published on: February 28, 2018

8.1K

Myocarditis and inflammatory cardiomyopathy: from diagnosis to treatment

Felicitas Escher1, Carsten Tschöepe2, Dirk Lassner3

  • 1Institute for Cardiac Diagnostics and Therapy (IKDT), Berlin, Germany; Department of Cardiology, Campus Virchow Klinikum, Charite - Universitaetsmedizin Berlin, Berlin, Germany. heinz-peter.schultheiss@charite.de.

Turk Kardiyoloji Dernegi Arsivi : Turk Kardiyoloji Derneginin Yayin Organidir
|December 31, 2015
PubMed

Insights

Myocarditis, an inflammation of the heart muscle, and inflammatory cardiomyopathy, which includes cardiac dysfunction, have uncertain incidences. Myocarditis can lead to dilated cardiomyopathy and carries a variable prognosis.

Area of Science:

  • Cardiology
  • Pathology

Background:

  • Myocarditis is defined as myocardial inflammation meeting specific diagnostic criteria.
  • Inflammatory cardiomyopathy is diagnosed when myocarditis is associated with cardiac dysfunction.

Purpose of the Study:

  • To determine the actual incidences of myocarditis and inflammatory cardiomyopathy.
  • To review the prevalence and prognosis of myocarditis.

Main Methods:

  • Review of studies on sudden cardiac death in young people.
  • Analysis of biopsy-proven myocarditis in adult patients with unexplained nonischemic dilated cardiomyopathy.

Main Results:

  • Autopsy prevalence of myocarditis in sudden cardiac death cases ranges widely from 2-42%.
  • Biopsy-proven myocarditis is found in 9-16% of adults with unexplained nonischemic dilated cardiomyopathy.
  • Up to 30% of biopsy-proven myocarditis cases may progress to dilated cardiomyopathy with a poor prognosis.

Conclusions:

  • The exact incidence of myocarditis and inflammatory cardiomyopathy remains challenging to ascertain.
  • Prognosis in myocarditis is variable and depends on the underlying cause and potential progression to dilated cardiomyopathy.

More Related Videos

Noninvasive Assessment of Cardiac Abnormalities in Experimental Autoimmune Myocarditis by Magnetic Resonance Microscopy Imaging in the Mouse12:24

Noninvasive Assessment of Cardiac Abnormalities in Experimental Autoimmune Myocarditis by Magnetic Resonance Microscopy Imaging in the Mouse

Published on: June 20, 2014

10.5K
Flow Cytometry-Based Quantification and Analysis of Myocardial B-Cells12:46

Flow Cytometry-Based Quantification and Analysis of Myocardial B-Cells

Published on: August 17, 2022

3.2K

Related Concept Videos

Myocarditis II: Clinical Features and Diagnostic Tests01:27

Myocarditis II: Clinical Features and Diagnostic Tests

Myocarditis is an inflammation of the heart muscle. The symptoms vary widely, encompassing asymptomatic presentations to severe, acute manifestations.Clinical PresentationAsymptomatic cases: In some instances, myocarditis may be asymptomatic, with the infection resolving without intervention. These cases often go undetected unless discovered incidentally through diagnostic imaging or tests conducted for other reasons.General Early Symptoms: Early symptoms of myocarditis are non-specific and can...
445
Myocarditis I: Introduction01:21

Myocarditis I: Introduction

Myocarditis is inflammation of the myocardium, which is the muscular layer of the heart.EtiologyMyocarditis has a diverse etiology, including a wide range of infectious and non-infectious causes:Infectious CausesViral: Common viruses include Coxsackie A and B, adenovirus, parvovirus B19, enteroviruses, and influenza A.Bacterial: Examples include infections caused by Streptococcus, Staphylococcus, and Mycoplasma species.Rickettsial: Infections like Rocky Mountain spotted fever can result in...
568
Myocarditis III: Medical Management01:14

Myocarditis III: Medical Management

Myocarditis: Comprehensive Medical ManagementMyocarditis, the heart muscle inflammation, requires a comprehensive medical management strategy that addresses the underlying cause, provides supportive care, manages symptoms, and reduces cardiac workload.Infections and Autoimmune CausesAdminister appropriate antimicrobial therapy when an infectious agent causes myocarditis. For instance, penicillin treats infections caused by Group A Streptococcus. In cases where autoimmune processes are...
318
Myocarditis IV: Nursing Management01:22

Myocarditis IV: Nursing Management

Myocarditis is an inflammatory condition of the myocardium requiring meticulous nursing management for optimal patient outcomes. Effective management begins with a thorough assessment of the patient's medical history, paying close attention to past infections, autoimmune disorders, travel history, and exposure to toxins or drugs. Recent viral infections and systemic diseases are particularly relevant due to their potential role in triggering myocarditis.Physical Examination and MonitoringThe...
350
Cardiomyopathy V: Interprofessional Care01:29

Cardiomyopathy V: Interprofessional Care

Managing cardiomyopathy involves addressing underlying or precipitating causes, treating heart failure with medications, and implementing dietary changes and a balanced exercise and rest regimen.Lifestyle ModificationsCardiomyopathy patients should adopt a low-sodium diet to reduce fluid retention and manage heart failure. A personalized exercise and rest plan helps maintain physical fitness without overstraining the heart. Avoiding alcohol and tobacco is essential to prevent further damage to...
621
Cardiomyopathy III: Hypertrophic Cardiomyopathy01:29

Cardiomyopathy III: Hypertrophic Cardiomyopathy

Hypertrophic cardiomyopathy, or HCM, is an autosomal dominant genetic disorder characterized by asymmetric left ventricular hypertrophy without ventricular dilation. It is more common in men and is typically diagnosed in young, athletic adults.EtiologyHCM is primarily genetic and is caused by mutations in genes encoding sarcomeric proteins. Researchers have identified over 1400 mutations across at least 11 different genes. Among these, the most frequently occurring mutations are found in the...
687