Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Development of Human Microbiota

Development of Human Microbiota

The human microbiota begins developing at birth and undergoes continual change as we age. Infancy marks a critical period of microbial sensitivity, offering a “window of opportunity” during which beneficial microbes help mature the immune system. By age three, children typically develop a more stable and diverse microbial community. Newborns acquire microbes from their immediate environment; vaginal delivery favors maternal vaginal microbes, while cesarean births favor microbes from...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Qualitative analyses of contributing factors to central line-associated bloodstream infections and catheter-associated urinary tract infections during the COVID-19 pandemic.

American journal of infection control·2026

Same author

Prospective validation and implementation of a model to identify patients with carbapenem-resistant Enterobacterales (CRE) carriage on admission to acute care hospitals.

Infection control and hospital epidemiology·2026

Same author

The changing landscape of outpatient antibiotic prescriptions among advanced practice clinicians in the United States, 2011 and 2022.

Antimicrobial stewardship & healthcare epidemiology : ASHE·2026

Same author

Association Between Peer Comparison Feedback and Hospitalist Antibiotic Prescribing.

JAMA network open·2026

Same author

Amoxicillin-Clavulanate vs Amoxicillin for Acute Sinusitis in Adults.

JAMA·2026

Same author

Treatment of multidrug-resistant Gram-negative infections: a stewardship imperative.

The Lancet. Infectious diseases·2026

Same journal

Simulation-based outbreak training and large language models in infection prevention and control education.

American journal of infection control·2026

Same journal

Identifying health care provider, system, and resource-related factors associated with CLABSIs in ICUs of LMICs: A Scoping Review.

American journal of infection control·2026

Same journal

Quantitative Assessment of Environmental Blood Contamination in Interventional Radiology Operating Rooms: A Cross-Sectional Study.

American journal of infection control·2026

Same journal

Rural-urban disparities in the receipt of seasonal influenza and COVID-19 vaccines.

American journal of infection control·2026

Same journal

Common Reasons for Overuse of Non-Sterile Gloves Across Different Healthcare Settings.

American journal of infection control·2026

Same journal

Hygiene and virucidal interventions in Ebola virus (Bundibugyo virus) and hantavirus (Andes virus) infection control: Translating laboratory evidence into practice.

American journal of infection control·2026

See all related articles

Search research articles

Related Experiment Video

Updated: Mar 28, 2026

An Ex vivo Assay to Study Candida albicans Hyphal Morphogenesis in the Gastrointestinal Tract

An Ex vivo Assay to Study Candida albicans Hyphal Morphogenesis in the Gastrointestinal Tract

Published on: July 1, 2020

Decrease in Candida bloodstream infections in veterans in Atlanta.

Sarah Kabbani¹, Jesse T Jacob¹, Robert P Gaynes²

¹Emory University School of Medicine, Atlanta, GA.

American Journal of Infection Control

|January 1, 2016

Summary

This summary is machine-generated.

Rates of Candida bloodstream infections in adults have recently declined. This decrease coincided with new infection control policies focused on central venous catheter maintenance, not antibiotic use.

Keywords:

Candidemia bloodstream infections

More Related Videos

A Soluble Tetrazolium-Based Reduction Assay to Evaluate the Effect of Antibodies on Candida tropicalis Biofilms

A Soluble Tetrazolium-Based Reduction Assay to Evaluate the Effect of Antibodies on Candida tropicalis Biofilms

Published on: September 16, 2022

A Contemporary Warming/Restraining Device for Efficient Tail Vein Injections in a Murine Fungal Sepsis Model

A Contemporary Warming/Restraining Device for Efficient Tail Vein Injections in a Murine Fungal Sepsis Model

Published on: November 6, 2020

Related Experiment Videos

Last Updated: Mar 28, 2026

An Ex vivo Assay to Study Candida albicans Hyphal Morphogenesis in the Gastrointestinal Tract

An Ex vivo Assay to Study Candida albicans Hyphal Morphogenesis in the Gastrointestinal Tract

Published on: July 1, 2020

A Soluble Tetrazolium-Based Reduction Assay to Evaluate the Effect of Antibodies on Candida tropicalis Biofilms

A Soluble Tetrazolium-Based Reduction Assay to Evaluate the Effect of Antibodies on Candida tropicalis Biofilms

Published on: September 16, 2022

A Contemporary Warming/Restraining Device for Efficient Tail Vein Injections in a Murine Fungal Sepsis Model

A Contemporary Warming/Restraining Device for Efficient Tail Vein Injections in a Murine Fungal Sepsis Model

Published on: November 6, 2020

Area of Science:

Infectious Diseases
Public Health
Healthcare Epidemiology

Background:

Healthcare-associated infections (HAIs) remain a significant concern.
Candida bloodstream infections (CBI) in adults have shown persistent, unchanged rates despite prevention efforts.
The role of specific interventions in reducing CBI requires further investigation.

Purpose of the Study:

To investigate the factors contributing to recent changes in adult Candida bloodstream infection rates.
To determine if infection control policies targeting central venous catheter maintenance correlate with a decline in CBI.
To assess the impact of these policies independent of broad-spectrum antibiotic usage.

Main Methods:

Retrospective analysis of adult patient data.
Monitoring of Candida bloodstream infection incidence.
Evaluation of infection control policy implementation, specifically central venous catheter maintenance protocols.
Analysis of concurrent broad-spectrum antibiotic prescribing trends.

Main Results:

A notable decline in adult Candida bloodstream infections was observed.
This decline was not associated with changes in broad-spectrum antibiotic use.
The reduction in CBI rates coincided temporally with the implementation of enhanced central venous catheter maintenance policies.

Conclusions:

Enhanced infection control policies for central venous catheter maintenance may be effective in reducing Candida bloodstream infections in adults.
These findings suggest a targeted approach to infection control can impact HAI rates.
Further research is warranted to confirm causality and explore the mechanisms behind this observed decline.