Venous thromboembolism in Croatia - Croatian Cooperative Group for Hematologic Diseases (CROHEM) study

Dražen Pulanić1, Velka Gverić-Krečak, Zlatka Nemet-Lojan

  • 1Dražen Pulanić, Kišpatićeva 12, 10000 Zagreb, Croatia, dpulanic@yahoo.com.

Croatian Medical Journal
|January 1, 2016
PubMed

Insights

The incidence of venous thromboembolism (VTE) in Croatia was estimated at 1.185 per 1000 people. Improved thromboprophylaxis for secondary VTE could significantly reduce its burden.

Area of Science:

  • Hematology
  • Epidemiology
  • Public Health

Background:

  • Venous thromboembolism (VTE) is a significant global health concern.
  • Understanding VTE incidence and characteristics is crucial for public health strategies.
  • Previous data on VTE in Croatia is limited.

Purpose of the Study:

  • To determine the incidence and characteristics of VTE in Croatia.
  • To compare VTE patient demographics and risk factors with international studies.
  • To identify potential areas for improving VTE prevention and management.

Main Methods:

  • An observational, non-interventional study was conducted in 2011.
  • Medical records of newly diagnosed VTE patients from four Croatian counties were reviewed.
  • The study population represented 13.1% of the Croatian population.

Main Results:

  • 663 VTE cases were identified: 61.5% deep vein thrombosis, 33% pulmonary embolism.
  • The median age was 71 years, with 56.3% female patients.
  • Secondary VTE (57.3%) was often linked to cancer (40.8%) or immobility (38.2%).
  • The estimated VTE incidence was 1.185 per 1000 people.
  • 10.6% of patients died, with VTE as the primary cause in 50% of these deaths.

Conclusions:

  • VTE characteristics in Croatia align with international findings.
  • Enhanced thromboprophylaxis in patients with risk factors for secondary VTE is recommended.
  • Implementing improved preventive measures could substantially decrease the VTE burden in Croatia.
Abstract

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