Related Experiment Videos
Extracorporeal shock wave lithotripsy in infants less than 12-month old
Burak Turna1, Ali Tekin2, İsmail Yağmur2
1Department of Urology, Ege University School of Medicine, Bornova, 35100, İzmir, Turkey. burakturna@gmail.com.
Insights
Extracorporeal shock wave lithotripsy (SWL) is safe and effective for treating infant kidney stones. Mid-term follow-up showed no new hypertension or diabetes, with normal kidney sizes in treated infants.
Area of Science:
- Pediatric Urology
- Nephrology
- Medical Devices
Background:
- Limited research exists on the long-term effects of extracorporeal shock wave lithotripsy (SWL) in infants.
- Infant kidney stones require safe and effective treatment options.
Purpose of the Study:
- To evaluate the efficacy and safety of SWL in infants under 12 months old.
- To assess potential mid-term adverse effects of SWL in this pediatric population.
Main Methods:
- Retrospective analysis of 36 infants (39 renal units) treated with SWL between 1999 and 2013.
- Mid-term follow-up included blood pressure, glucose levels, kidney size assessment, clinical exams, blood tests, and imaging.
Main Results:
- An 84.6% stone-free rate was achieved after 3 months with no major complications.
- Mid-term follow-up (mean 3.2 years) in 20 children revealed no new hypertension or diabetes.
- All treated infant kidneys remained within normal size percentiles.
Conclusions:
- SWL is an effective and safe treatment modality for kidney stones in infants.
- Mid-term outcomes suggest SWL does not lead to significant adverse health effects in young children.
Abstract:
There is a lack of literature on children compared to adults regarding the long-term effects of extracorporeal shock wave lithotripsy (SWL), specifically in infants. The aim of the present study was to analyze the efficacy and safety of SWL in infants and also evaluate its potential adverse effects in the mid-term. Between May 1999 and December 2013, 36 infants with 39 renal units underwent SWL treatment for kidney stones with an electrohydraulic lithotripter (Dornier MPL 9000/ELMED Multimed Classic). All children were less than 12-month old. The mid-term effects of SWL were examined at the last follow-up by measuring arterial blood pressure, random blood glucose level and ipsilateral kidney size. Evaluation of treatment and its consequences was based on clinical examination, blood tests and conventional imaging (plain abdominal radiography and ultrasound). Overall stone-free rate was 84.6 % after 3-month follow-up without any major complications. Mid-term follow-up was available in 20 of 36 children with a mean follow-up of 3.2 ± 2.8 years (range 0.5-15.3). None of the infants were found to develop new onset of hypertension or diabetes. All treated infant kidneys' sizes were in the normal percentile range. SWL for management of infant kidney stones is effective and safe in the mid-term.