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Castleman's disease: a well defined histological pattern for a widely divergent clinical spectrum
M F d'Agay1, J M Miclea, J P Clauvel
1Laboratoire d'Anatomie Pathologique, Hôpital Saint-Louis, Paris, France.
Nouvelle Revue Francaise D'Hematologie
|January 1, 1989
Abstract:
If the histological patterns of Castleman's disease are well defined--hyaline vascular type and plasma cell type--, the clinical spectrum is widely divergent, ranging from localised forms cured by surgical ablation to multicentric idiopathic forms requiring systemic therapy; some cases are associated with an acquired immunodeficiency, such as HIV infection. The pathogeny of the disease is discussed.