Related Experiment Video
Updated: Mar 28, 2026
Occlusion of the Great and Small Saphenous Vein Using Copolymeric Glue Based on N-Butyl Cyanoacrylate and Methacryloxy Sulfolane
Published on: December 9, 2022
Venous Leg Ulcer in a Sarcoidosis Patient: A Case Report
Jungyoon Ohn1, Sang Young Byun1, In Su Kim1
1Department of Dermatology, Seoul National University Bundang Hospital, Seongnam, Korea.
Insights
This study suggests that patients with sarcoidosis may be more susceptible to developing venous leg ulcers. Histologic findings indicate a link between sarcoidosis, fibrin deposition, and these common leg ulcers.
Area of Science:
- Dermatology
- Rheumatology
- Pathology
Background:
- Venous leg ulcers are common, with pericapillary fibrin cuffs implicated in their pathogenesis.
- Sarcoidosis is a systemic granulomatous disease characterized by widespread fibrin deposition.
Abstract:
Venous leg ulcers, the most common form of leg ulcers, are relevant to the pathogenicity of pericapillary fibrin cuff. Sarcoidosis, a multiorgan granulomatous disease, causes fibrin deposition in tissues. We report a case of a 50-year-old man with venous leg ulcers coexisting with sarcoidosis. On the basis of the histologic findings, we propose the hypothesis that sarcoidosis patients are prone to the development of venous leg ulcers.
