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Updated: Mar 28, 2026

Breathing-controlled Electrical Stimulation BreEStim for Management of Neuropathic Pain and Spasticity
Published on: January 10, 2013
Effect of a combined continuous and intermittent transcutaneous electrical nerve stimulation on pain perception of
Irma Pérez-Ruvalcaba1, Viridiana Sánchez-Hernández1, Arieh R Mercado-Sesma2
1Burn Unit, Hospital de Especialidades, Centro Médico Nacional de Occidente, Mexican Institute of Social Security, Guadalajara, Mexico.
Aim:
The aim of this study was to assess the effect of continuous and intermittent electrical transcutaneous nerve stimulation on the perception of pain in patients with burns of different types.
Materials And Methods:
A pilot study was conducted in 14 patients (age 30.9±7.5 years) with second- and third-degree burns of different types. The burn types included electrical, fire/flame, and chemical. All patients received continuous and intermittent electrical transcutaneous nerve stimulation sessions three times per week for 4 weeks. Each session had a duration of 30 minutes. A pair of electrodes were placed around the burn. The primary efficacy endpoint was the perception of pain assessed by a visual analog scale at baseline and at the 30th day.
Results:
A significant reduction of pain perception was reported (8.0±1.7 vs 1.0±0.5; P=0.027) by all patients after electrical stimulation therapy. There were no reports of adverse events during the intervention period.
Conclusion:
Electrical stimulation could be a potential nonpharmacological therapeutic option for pain management in burn patients.

