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A Protocol for Analyzing Hepatitis C Virus Replication
Published on: June 26, 2014
SOCIO-DEMOGRAPHIC STUDY OF HEPATITIS C PATIENTS VISITING TERTIARY CARE HOSPITAL
Insights
Hepatitis C infection disproportionately affects females in Pakistan, particularly married women experiencing emotional distress and behavioral changes shortly after diagnosis. This highlights a need for targeted support for vulnerable populations.
Area of Science:
- Hepatology
- Public Health
- Epidemiology
Background:
- Hepatitis C (HCV) is a prevalent blood-borne liver disease.
- HCV infection can lead to severe liver conditions like cirrhosis and hepatocellular carcinoma.
- Understanding the sociodemographic profile of HCV patients is crucial for public health interventions.
Purpose of the Study:
- To determine the sociodemographic status of Hepatitis C patients in Lahore, Pakistan.
- To identify potential risk factors and associations within the HCV-infected population.
- To inform targeted public health strategies for Hepatitis C management.
Main Methods:
- A cross-sectional study was conducted in October-November 2009.
- 154 volunteer Hepatitis C Virus (HCV) patients were enrolled.
- Sociodemographic variables were analyzed using SPSS-15.
Main Results:
- Females constituted a high percentage (70.1%) of the study population.
- The majority of patients were from labor occupations (39.4%), with a significant portion being illiterate (71.4%).
- Gender and marital status showed significant associations with sleep disturbance, tension, and emotional/behavioral changes (p<0.05).
Conclusions:
- Hepatitis C incidence was higher among females.
- Married females diagnosed more recently experienced greater depression and behavioral changes.
- Sociodemographic factors play a significant role in the psychological impact of Hepatitis C.
Background:
Hepatitis C is a very common blood-borne disease of liver caused by Hepatitis C Virus and about two third of these patients will ultimately end up having liver cirrhosis or hepatocellular carcinoma. This study was carried out to determine the sociodemographic status of the hepatitis C infected patients visiting tertiary care hospitals in Lahore, Pakistan.
Methods:
This study was conducted during the months of October and November 2009. In this cross sectional study, 154 volunteer patients of HCV were included. They were investigated for sociodemographic variables and were statistically analysed by SPSS-15.
Results:
Of these 154 patients, a high percentage of patients were females (70.1%). Majority of the patients belonged to the families of labour occupation (39.4%) of which 71.4 % were illiterate. Gender was found significantly associated with categories of sleep disturbance (p<0.05) and tension (p<0.05) among HCV patients. Married patients were significantly associated with tension (p<0.05) and a significant emotional and behavioural change in their attitude was also found (p<0.05). Patients with shorter interval after first diagnosis of the disease felt more emotional and had greater behavioural changes in their attitude (p<0.05).
Conclusion:
Incidence of Hepatitis C was higher in females and married females with shorter interval after first diagnosis of the disease were more depressed.
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