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Symbiotic relationships are long-term, close interactions between individuals of different species that affect the distribution and abundance of those species. When a relationship is beneficial to both species, this is called mutualism. When the relationship is beneficial to one species but neither beneficial nor harmful to the other species, this is called commensalism. When one organism is harmed to benefit another, the relationship is known as parasitism. These types of relationships often...
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Cytomegalovirus (CMV) disease is caused by human cytomegalovirus, a double-stranded DNA virus of the Herpesviridae family. While primary CMV infection is often asymptomatic in immunocompetent individuals, the virus can cause severe disease in neonates and immunocompromised patients. CMV is the most common cause of congenital viral infection in the United States, and a major pathogen in solid organ and hematopoietic stem cell transplant recipients.CMV is transmitted via bodily fluids, sexual...
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Phenylketonuria (PKU) is a protein metabolism disorder characterized by high blood levels of the amino acid phenylalanine. This results from a mutation in the gene responsible for phenylalanine hydroxylase, an enzyme that converts phenylalanine into tyrosine. When this enzyme is deficient, phenylalanine builds up in the blood, leading to symptoms such as vomiting, rashes, seizures, growth deficiency, and severe mental retardation. An early diagnosis and a diet restricting phenylalanine intake...
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Author Spotlight: Identifying Compensatory Pathways in Malaria Parasites Containing Hypomorphic Allele of Essential Protein Kinases
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CONGENITAL MALARIA.

Sajid Ali Shah, Zeeshan Ahmed, Munir Akmal Lodhi

    Journal of Ayub Medical College, Abbottabad : JAMC
    |January 2, 2016
    PubMed
    Summary

    Congenital malaria in neonates can mimic sepsis, delaying diagnosis and increasing risks. This case highlights a premature infant with mixed malarial infection and congenital adrenal hyperplasia, emphasizing diagnostic challenges.

    Area of Science:

    • Neonatology
    • Infectious Diseases
    • Pediatric Endocrinology

    Background:

    • Congenital malaria presents with non-specific symptoms in neonates, often misdiagnosed as sepsis or inborn errors of metabolism.
    • Delayed diagnosis of congenital malaria leads to significant mortality and morbidity in newborns.
    • Mixed malarial infections can complicate diagnosis and treatment in the neonatal period.

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