[Metabolic studies in 2 cases of chondrocalcinosis with hypomagnesemia]

Two cases of chondrocalcinosis associated with hypomagnesemia are presented and a literature review is carried out, revealing that half of the reported cases are associated with Bartter Syndrome. We describe the metabolic studies performed and discuss the possible role of calciotrope hormones in this type of clinical manifestation. The pathogenesis is thought to be a defect in the transport across the renal tubular cell (and also, possibly an alteration in the intestinal epithelial membrane) as well as the presence of other metabolic alterations (hypocalcemia, hypokalemia, hydrocarbon intolerance) associated with this not so rare disease.