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Updated: Mar 28, 2026
07:01
An Orthotopic Mouse Model of Anaplastic Thyroid Carcinoma
Published on: April 17, 2013
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Choriocarcinoma presenting with thyrotoxicosis.
David Sotello1, Ana Marcella Rivas1, Victor J Test1
1Department of Internal Medicine (Sotello, Rivas), Division of Pulmonary/Critical Care Medicine (Test), and Division of Endocrinology (Lado-Abeal), Texas Tech University Health Science Center, Lubbock, Texas.
Proceedings (Baylor University. Medical Center)
|January 2, 2016
Summary
A young man with metastatic choriocarcinoma experienced hyperthyroidism due to elevated beta-human chorionic gonadotropin (B-HCG). Chemotherapy resolved B-HCG levels and thyroid dysfunction, demonstrating a direct link between B-HCG and hyperthyroidism.
Area of Science:
- Endocrinology
- Oncology
- Pulmonology
Background:
- Metastatic choriocarcinoma can present with unusual systemic effects.
- Elevated beta-human chorionic gonadotropin (B-HCG) is a hallmark of gestational trophoblastic disease, including choriocarcinoma.
- Hyperthyroidism is a rare but serious complication of highly elevated B-HCG levels.
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