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Related Experiment Videos

Experimental models in drug development for helminthic diseases.

J C Katiyar1, S Gupta, S Sharma

  • 1Central Drug Research Institute, Lucknow, India.

Reviews of Infectious Diseases
|July 1, 1989
PubMed
Summary

Helminthic infections pose a global health challenge, especially in tropical regions. This review covers the uses and features of available anthelmintics, crucial for combating these parasitic worm infections.

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Area of Science:

  • Parasitology
  • Tropical Medicine
  • Pharmacology

Background:

  • Helminthic infections are a significant global health issue, particularly impacting tropical regions with poor sanitation and limited health education.
  • These infections have considerable socioeconomic consequences worldwide.
  • Despite challenges, progress in anthelmintic drug development and research models exists.

Purpose of the Study:

  • To review the current uses of anthelmintics.
  • To describe the pharmacologic and clinical features of various anthelmintic drugs.
  • To provide an overview of available treatment options for helminthic infections.

Main Methods:

  • Literature review of existing research on anthelmintics.
  • Analysis of pharmacologic data for anthelmintic agents.

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  • Compilation of clinical features and uses of approved and experimental anthelmintics.
  • Main Results:

    • A range of anthelmintics are available for treating helminthic infections.
    • Each anthelmintic possesses distinct pharmacologic and clinical profiles.
    • Model systems aid in the ongoing development of new treatments.

    Conclusions:

    • Anthelmintics are essential tools for managing helminthic infections globally.
    • Understanding the specific uses and features of each drug is critical for effective treatment.
    • Continued research and development are vital to address the persistent burden of helminthiasis.