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Updated: Jan 25, 2026

Simplified Reverse Genetics Method to Recover Recombinant Rotaviruses Expressing Reporter Proteins
Published on: April 17, 2020
[Anti-rotavirus and intussusception: no evidence to discontinue the universal vaccination policy]
Paolo Bonanni1, Carlo Signorelli2
1Dipartimento di Scienze della Salute, Università di Firenze, Italia.
Abstract:
This report analyses the serious side effects of rotavirus vaccine with particular regard to intussusception, especially in light of the reasons which prompted the French health authorities to suspend, in April 2015, the previously approved recommendation of universal vaccination. Considering the current scientific evidence and the well motivated guidelines set by other European countries, the authors conclude that there are no reasons at the present time to suspend the universal offer of anti-rotavirus vaccination to infants, since it shows a favourable benefit-risk ratio and it is characterized by an excellent cost-effectiveness profile.
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