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Updated: Mar 28, 2026

Handwriting Analysis Indicates Spontaneous Dyskinesias in Neuroleptic Naïve Adolescents at High Risk for Psychosis
Published on: November 21, 2013
Fluctuating dermatoglyphic asymmetries in youth at ultrahigh-risk for psychotic disorders
Olivia Diane Fern Russak1, Lindsay Ives2, Vijay A Mittal3
1University of California Los Angeles, Semel Institute for Neuroscience and Human Behavior, Los Angeles, CA, United States.
Abstract:
Fluctuating dermatoglyphic asymmetry represents one specific class of minor physical anomaly that has been proposed to reflect prenatal insult and vulnerability to psychosis. However, very little is known about fluctuating dermatoglyphic asymmetry in youth showing symptoms of ultrahigh risk (UHR) for psychosis. Using high-resolution photographs of fingerprints and clinical interviews, the UHR group in this study showed greater fluctuating dermatoglyphic asymmetry compared to controls; however, this was not further linked to symptomatology. The results of this study provide an important perspective on potential biomarkers and support neurodevelopmental conceptions of psychosis.
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