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[How to assess clinical practice guidelines with AGREE II: The example of neonatal jaundice]

L Renesme1, A Bedu2, P Tourneux3

  • 1Service de néonatologie, maternité, centre Aliénor-d'Aquitaine, CHU de Bordeaux, place Amélie-Raba-Léon, 33000 Bordeaux, France.

Archives De Pediatrie : Organe Officiel De La Societe Francaise De Pediatrie
|January 4, 2016
PubMed

Insights

Neonatal jaundice guidelines vary in quality. The UK

Area of Science:

  • Neonatal care
  • Clinical practice guidelines
  • Bilirubin metabolism

Background:

  • Neonatal jaundice affects 50-70% of newborns.
  • High bilirubin levels can cause kernicterus.
  • Lack of consensus on jaundice management exists globally.

Purpose of the Study:

  • To assess the quality of national clinical practice guidelines for neonatal jaundice.
  • To compare management strategies across different countries.

Main Methods:

  • Systematic literature review of national guidelines.
  • Quality assessment using the AGREE II tool by four independent reviewers.
  • Analysis of management modalities including screening, treatment, and follow-up.

Main Results:

  • Seven national guidelines were identified (South Africa, USA, UK, Canada, Norway, Switzerland, Israel).
  • Significant variation in guideline quality was observed based on AGREE II scores.
  • Clinical management approaches showed minimal differences across guidelines.

Conclusions:

  • The UK's NICE guideline demonstrated the highest quality according to AGREE II.
  • The AGREE II tool is recommended for developing future high-quality guidelines.
  • A national guideline is needed in France for standardized neonatal jaundice management.
Abstract

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