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Updated: Mar 28, 2026
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Doppler Optical Coherence Tomography of Retinal Circulation
Published on: September 18, 2012
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Proposal for a Vascular Computed Tomography-Based Grading System in Posterior Circulation Stroke: A Single-Center
Valerio Da Ros1, Alessandro Meschini1, Roberto Gandini1
1Department of Diagnostic Imaging and Interventional Radiology, University of Rome Tor Vergata, Rome, Italy.
Summary
Computed tomography angiography (CTA) shows prognostic value in mechanical thrombectomy for vertebrobasilar stroke. This posterior circulation CTA (pc-CTA) approach may aid in patient triage for better outcomes.
Area of Science:
- Neurology
- Radiology
- Interventional Neuroradiology
Background:
- Mechanical thrombectomy is a key treatment for acute vertebrobasilar stroke.
- Assessing treatment effectiveness and patient prognosis is crucial for optimizing outcomes.
Purpose of the Study:
- To investigate the prognostic role of a computed tomography angiography (CTA)-based approach in patients undergoing mechanical thrombectomy for vertebrobasilar stroke.
- To evaluate the correlation between posterior circulation CTA (pc-CTA) findings and clinical outcomes.
Main Methods:
- Retrospective analysis of 15 patients with acute vertebrobasilar stroke treated with mechanical thrombectomy.
- Evaluation of posterior circulation ASPECTS (pc-ASPECTS) on CTA and a 6-point pc-CTA vascular score assessing collateralization.
- Correlation of pc-CTA scores and pc-ASPECTS with modified Rankin Scale scores at 3 months.
Main Results:
- A lower pc-CTA score was significantly associated with a good clinical outcome (P = .02).
- Excellent interobserver agreement was found for pc-CTA (P = .001), unlike pc-ASPECTS (P = .21).
- Patency of the distal basilar artery and posterior cerebral arteries correlated with favorable outcomes.
Conclusions:
- The pc-CTA approach demonstrates prognostic value in patients with vertebrobasilar stroke undergoing mechanical thrombectomy.
- pc-CTA may serve as an additional prognostic triage tool for this patient subgroup.
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