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Using Adhesive Patterning to Construct 3D Paper Microfluidic Devices
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3D printed microfluidic circuitry via multijet-based additive manufacturing.

R D Sochol1, E Sweet, C C Glick

  • 1Department of Mechanical Engineering, University of California, Berkeley, USA.

Lab on a Chip
|January 5, 2016
PubMed
Summary
This summary is machine-generated.

Three-dimensional (3D) printing using multijet modeling enables complex microfluidic components like capacitors, diodes, and transistors. This advanced fabrication method enhances performance and opens new possibilities for on-chip automation in chemical and biological applications.

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Area of Science:

  • Microfluidics
  • Additive Manufacturing
  • Materials Science

Background:

  • Traditional microfabrication methods face challenges in scaling fluidic processors.
  • Three-dimensional (3D) printing, particularly stereolithography, shows promise for microfluidic component construction.
  • Current stereolithography lacks multi-material printing for sacrificial supports, limiting geometric complexity.

Purpose of the Study:

  • To investigate multijet modeling (polyjet printing) for fabricating complex 3D microfluidic components.
  • To evaluate the performance of 3D printed fluidic capacitors, diodes, and transistors.
  • To explore advancements in on-chip automation through geometric modification of fluidic components.

Main Methods:

  • Utilized multijet modeling (polyjet printing), a multi-material inkjetting process, for layer-by-layer fabrication.
  • Designed and printed fundamental microfluidic operators: fluidic capacitors, diodes, and transistors.
  • Conducted theoretical and experimental analyses to evaluate component performance.

Main Results:

  • 3D printed fluidic capacitors with non-planar diaphragms showed improved performance compared to planar designs.
  • 3D printed fluidic diodes exhibited a high diodicity of 80.6 ± 1.8, indicating efficient flow rectification.
  • 3D printed fluidic transistors achieved a pressure gain of 3.01 ± 0.78 through geometry-based enhancement.

Conclusions:

  • Multijet modeling is a viable technique for creating geometrically complex and functionally advantageous microfluidic components.
  • This 3D printing approach can advance on-chip automation and expand fluidic routing capabilities.
  • Digitally transferable 3D models and accessible printers can democratize advanced microfluidic research beyond core engineering fields.