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Updated: Mar 28, 2026

Collecting And Measuring Wound Exudate Biochemical Mediators In Surgical Wounds
Published on: October 20, 2012
[Roles of Inflammatory Reaction and Cytokines in Chronic Postsurgical Pain]
Ling Lan1, Le Shen1, Yu-guang Huang1
1Department of Anesthesiology,PUMC Hospital,CAMS and PUMC,Beijing 100730,China.
Abstract:
Chronic postsurgical pain (CPSP) is characterized by high incidence,prolonged duration,multiple risk factors,and complicated pathogenesis. It seriously impairs patients' quality of life,especially after thoracotomy. Perioperative nerve injury is a major cause of CPSP. Meanwhile,the excessive neuroinflammation and inflammatory cytokines caused by surgery also accelerate the formation of CPSP. This review aims to provide an overview of the recent advances in the roles of inflammatory reaction and cytokines in the development of CPSP.
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