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[Splanchnic venous thrombosis: A monocentric study of 31 cases]
1Service de médecine interne, CHU Mohamed VI, faculté de médecine et de pharmacie, université Cadi Ayyad, Marrakech, Maroc.
Insights
Splanchnic vein thrombosis (SVT) often indicates underlying prothrombotic states or diseases. Identifying these conditions is crucial for effective treatment and preventing fatal complications in patients with SVT.
Area of Science:
- Internal Medicine
- Vascular Medicine
- Hematology
Background:
- Splanchnic vein thrombosis (SVT) involves the hepatic and extrahepatic portal systems.
- SVT frequently signifies underlying prothrombotic states.
- Therapeutic management of SVT can be complex.
Purpose of the Study:
- To analyze epidemiological, clinical, laboratory, therapeutic, and outcome data of SVT cases.
- To identify common etiologies and clinical presentations of SVT.
- To evaluate treatment strategies and patient outcomes in SVT.
Main Methods:
- Monocentric study of 31 SVT cases.
- Data collected between January 2006 and June 2012.
- Analysis of patient data including demographics, symptoms, laboratory findings, treatments, and outcomes.
Main Results:
- SVT showed a slight female predominance, with a median age of 37 years.
- Chronic SVT (61.2%) presented with portal hypertension signs, while acute SVT showed abdominal pain.
- Behçet's disease was the most common etiology (32%); treatment involved anticoagulants, corticosteroids, and immunosuppressants, with a 16% mortality rate.
Conclusions:
- SVT often indicates an underlying disease or prothrombotic state requiring identification.
- Tailoring treatment based on identified etiologies is essential.
- Early diagnosis and appropriate management of SVT can help avoid severe complications.
Introduction:
Splanchnic vein thrombosis (SVT) denotes thrombosis of the hepatic venous system and of the extrahepatic portal system. They are often the manifestation of one or more underlying prothrombotic states and can sometimes present problems of therapeutic care.
Methods:
We report a monocentric study of 31 cases of SVT observed in an internal medicine department between January 2006 and June 2012. Epidemiological, clinical, laboratory, therapeutic and outcome data were analyzed.
Results:
There was a slight female predominance (sex-ratio: 1.2). Median patient age at diagnosis was 37 years. Most cases of SVT were chronic (61.2%). Abdominal pain was the predominant symptom in acute cases while the predominant signs in chronic forms were signs of portal hypertension. Extrasplanchnic thrombosis was noted in seven patients (22.5%). Behçet's disease was the most common etiology (32%). The treatment was based on anticoagulants and corticosteroids and immunosuppressants when an inflammatory etiology was found. The average follow-up was 17 months. There were five deaths (16%).
Conclusion:
SVT often reflects the existence of a disease and/or an underlying prothrombotic state that should be identified to adapt the treatment and to avoid fatal complications.
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