Insights into acute myeloid leukemia via single cell network profiling
Steven M Kornblau1, Mark D Minden2, Donna Hogge3
1MD Anderson Cancer Center, University of Texas, 1515 Holcombe Blvd, Box 448, Houston, TX 77030-4095, USA.
Abstract:
Single Cell Network Profiling (SCNP) uses multi-parameter flow cytometry to simultaneously measure resting and evoked intracellular signalling molecules and pathways in distinct cell subsets within a complex tissue sample. This review focuses on the utility of SCNP and its potential applications for chemotherapy selection in Acute Myeloid Leukemia (AML).
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