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Night-time home versus ambulatory blood pressure in determining target organ damage

Emmanuel A Andreadis1, Gerasimos Agaliotis, Anastasios Kollias

  • 1aFourth Department of Medicine, Evangelismos General Hospital bHypertension Center, STRIDE-7, Third University Department of Medicine, Sotiria Hospital, Athens, Greece.

Journal of Hypertension
|January 5, 2016
PubMed

Insights

Night-time blood pressure (BP) measured at home is as effective as ambulatory monitoring for detecting early organ damage in untreated hypertension. This finding supports home BP monitoring for assessing cardiovascular risk.

Area of Science:

  • Cardiology
  • Hypertension Research
  • Diagnostic Monitoring

Background:

  • Untreated hypertension poses a risk for preclinical target organ damage.
  • Accurate BP monitoring is crucial for assessing this risk.

Purpose of the Study:

  • To compare the effectiveness of home blood pressure (HBP) monitoring versus ambulatory blood pressure (ABP) monitoring in assessing night-time BP.
  • To evaluate the association of night-time BP, measured by HBP or ABP, with preclinical target organ damage in untreated hypertensive individuals.

Main Methods:

  • 131 untreated hypertensive participants underwent 24-hour ABP monitoring.
  • Home blood pressure monitoring included daytime and night-time measurements over several days.
  • Target organ damage was assessed using left ventricular mass index (LVMI), common carotid intima-media thickness (cIMT), urine albumin excretion (UAE), and ankle-brachial index (ABI).

Main Results:

  • Strong correlations were observed between daytime and night-time ABP and HBP measurements.
  • Both night-time ABP and HBP showed significant correlations with all assessed indices of preclinical target organ damage.
  • Night-time systolic HBP was a significant determinant of LVMI, cIMT, and UAE, comparable to night-time ABP.

Conclusions:

  • Night-time blood pressure assessment using home monitoring is a reliable alternative to ambulatory monitoring for identifying preclinical target organ damage in untreated hypertension.
  • Home blood pressure monitoring can effectively aid in the risk stratification of hypertensive patients.
Abstract

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