Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Regulated mRNA Transport

Regulated mRNA Transport

In eukaryotes, transcription and translation are compartmentalized; an mRNA is first synthesized in the nucleus and then selectively transported to the cytoplasm for protein synthesis. Before transport, a pre-mRNA undergoes several steps of post-transcriptional modifications including splicing, 5' capping, and the addition of a poly-adenine tail. Various proteins bind to the pre-mRNA during these modifications. The mRNA transport takes place with the help of multiple proteins playing...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Population-level interventions for dementia prevention: a systematic review.

The lancet. Healthy longevity·2026

Same author

Impact of plasma pTau181 levels on clinician diagnostic confidence and management in memory and cognition clinics: A multi-site before-and-after study.

Alzheimer's & dementia (Amsterdam, Netherlands)·2026

Same author

Microfluidic co-culture system for synaptically segregated neural networks to explore astrocyte-driven neural pathology.

Microsystems & nanoengineering·2026

Same author

Regional and Socioeconomic Disparities in Frailty Across Tasmania: Evidence From Island Study Linking Ageing and Neurodegenerative Disease.

Australasian journal on ageing·2026

Same author

Cofilin hyperphosphorylation triggers TDP-43 pathology in sporadic amyotrophic lateral sclerosis.

Brain : a journal of neurology·2026

Same author

The Role of the Golgi Apparatus in Neurodegeneration.

Sub-cellular biochemistry·2026

Same journal

Molecular characteristics of isocitrate dehydrogenase 1 R132C-mutant diffuse gliomas: association with TP53 alterations and Li-Fraumeni syndrome.

Acta neuropathologica communications·2026

Same journal

Phenotype-specific muscle proteomic profiling in titinopathies.

Acta neuropathologica communications·2026

Same journal

MET-associated immune prognostic signature predicts survival and guides personalized therapy in glioma.

Acta neuropathologica communications·2026

Same journal

Nanopore-based DNA methylation profiling for rapid molecular classification of NOS/NEC CNS tumors: multi-institutional evaluation using FFPE archives and frozen tissues.

Acta neuropathologica communications·2026

Same journal

Correction to: Induction of CNS α-synuclein pathology by fibrillar and non-amyloidogenic recombinant α-synuclein.

Acta neuropathologica communications·2026

Same journal

A rare missense variant impacting NEK1 kinase function is associated with ALS.

Acta neuropathologica communications·2026

See all related articles

Search research articles

Related Experiment Video

Updated: Mar 28, 2026

A Novel Strategy Combining Array-CGH, Whole-exome Sequencing and In Utero Electroporation in Rodents to Identify Causative Genes for Brain Malformations

A Novel Strategy Combining Array-CGH, Whole-exome Sequencing and In Utero Electroporation in Rodents to Identify Causative Genes for Brain Malformations

Published on: December 1, 2017

Erratum: C9ORF72 expression and cellular localization over mouse development.

Rachel A K Atkinson¹, Carmen M Fernandez-Martos¹, Julie D Atkin²

¹Wicking Dementia Research and Education Centre, Faculty of Health, University of Tasmania, Hobart, Tasmania, Australia.

Acta Neuropathologica Communications

|January 6, 2016

Summary

This summary is machine-generated.

This correction clarifies the specific antibodies used in protein extraction and western blot analysis. The updated methods ensure accurate replication of research on C9ORF72 and GAPDH protein levels.

Area of Science:

Biochemistry
Molecular Biology
Neuroscience

More Related Videos

Author Spotlight: Imaging ATG9A, a Multi-Spanning Membrane Protein

Author Spotlight: Imaging ATG9A, a Multi-Spanning Membrane Protein

Published on: June 16, 2023

An Integrated Approach for Microprotein Identification and Sequence Analysis

An Integrated Approach for Microprotein Identification and Sequence Analysis

Published on: July 12, 2022

Related Experiment Videos

Last Updated: Mar 28, 2026

A Novel Strategy Combining Array-CGH, Whole-exome Sequencing and In Utero Electroporation in Rodents to Identify Causative Genes for Brain Malformations

A Novel Strategy Combining Array-CGH, Whole-exome Sequencing and In Utero Electroporation in Rodents to Identify Causative Genes for Brain Malformations

Published on: December 1, 2017

Author Spotlight: Imaging ATG9A, a Multi-Spanning Membrane Protein

Author Spotlight: Imaging ATG9A, a Multi-Spanning Membrane Protein

Published on: June 16, 2023

An Integrated Approach for Microprotein Identification and Sequence Analysis

An Integrated Approach for Microprotein Identification and Sequence Analysis

Published on: July 12, 2022