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Near Infrared Photoimmunotherapy for Mouse Models of Pleural Dissemination
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Targeted phototherapy.

Venkataram Mysore1, B M Shashikumar

  • 1Department of Dermatology, Venkat Charmalaya - Centre for Advanced Dermatology, Bengaluru, Karnataka, India.

Indian Journal of Dermatology, Venereology and Leprology
|January 6, 2016
PubMed
Summary
This summary is machine-generated.

Targeted phototherapy, including excimer laser and lamp, is effective for vitiligo and psoriasis, especially for localized or resistant cases. Its use in other conditions lacks strong evidence.

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Area of Science:

  • Dermatology
  • Photomedicine
  • Medical Technology

Background:

  • Targeted phototherapy offers advantages over conventional methods for skin conditions.
  • This review examines various targeted phototherapy technologies and provides evidence-based recommendations.

Purpose of the Study:

  • To review the technologies and clinical evidence for targeted phototherapy.
  • To establish recommendations for the use of targeted phototherapy based on current evidence.

Main Methods:

  • A comprehensive literature search was conducted using PubMed, EMBASE, and Cochrane Library up to March 2014.
  • Keywords included "targeted phototherapy", "excimer laser", "excimer lamp", "vitiligo", and "psoriasis".
  • Systematic reviews, meta-analyses, guidelines, RCTs, and observational studies were included.

Main Results:

  • 24 out of 340 evaluated studies met the inclusion criteria for guideline development.
  • Targeted phototherapy demonstrated efficacy in treating vitiligo and psoriasis.

Conclusions:

  • Targeted phototherapy is beneficial for vitiligo and psoriasis, particularly for localized, resistant, or pediatric cases (Level 2+, Grade B).
  • Its application in other dermatological conditions requires further investigation due to limited evidence (Level 3+, Grade C).
  • Cost and practicality may limit its use to specific lesion types.