Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Continuous Renal Replacement Therapy01:30

Continuous Renal Replacement Therapy

1.8K
Continuous Renal Replacement Therapy, also known as CRRT, is a procedural treatment for acute kidney injury (AKI) that gradually removes uremic toxins and fluids while maintaining acid-base balance and stabilizing electrolytes. It is particularly useful for hemodynamically unstable patients. Unlike intermittent hemodialysis, which is faster, CRRT provides a gentler approach over 24 hours, closely mimicking the function of natural kidneys. However, CRRT is not ideal for patients with...
1.8K
Acute Kidney Injury V: Interprofessional Care01:20

Acute Kidney Injury V: Interprofessional Care

455
Acute Kidney Injury (AKI) requires a collaborative healthcare approach to restore renal function and prevent complications. Essential management strategies involve monitoring fluid and electrolyte balance, adjusting medications, initiating dialysis when necessary, and providing nutritional support.Fluid and Electrolyte ManagementFluid Monitoring: Regularly monitoring body weight, central venous pressure, and urine output helps detect fluid imbalances early. Patient intake and output are...
455
Extracorporeal Removal of Drugs: Continuous Renal Replacement Therapy01:26

Extracorporeal Removal of Drugs: Continuous Renal Replacement Therapy

339
Continuous Renal Replacement Therapy (CRRT) is an essential intervention for patients experiencing severe kidney dysfunction. This therapy offers a continuous mechanism for removing fluids and toxins from the bloodstream, leveraging the patient’s blood pressure to facilitate filtration through a specialized filter. This method contrasts with intermittent dialysis, providing a gentler and more consistent removal of waste products and excess fluid, which is particularly beneficial in...
339
Acute Kidney Injury IV: Diagnostic Studies and Prevention01:30

Acute Kidney Injury IV: Diagnostic Studies and Prevention

472
Accurate diagnosis and effective prevention are critical in managing Acute Kidney Injury (AKI), which is linked to high mortality rates ranging from 10% to 80%. Timely recognition of at-risk patients and careful monitoring can significantly reduce the likelihood of kidney damage.Diagnostic Assessments:The diagnostic process starts with a comprehensive medical history to identify prerenal, intrarenal, and postrenal causes.Prerenal causes, such as dehydration, hypotension, or blood loss, should...
472
Chronic Kidney Disease III: Interprofessional Care01:28

Chronic Kidney Disease III: Interprofessional Care

609
Chronic kidney disease (CKD) requires collaborative and comprehensive management. CKD progresses through stages and can lead to end-stage kidney disease (ESKD) if untreated. Interprofessional collaboration and patient education are crucial, enabling patients to manage their health and improve their quality of life.Diagnostic approach for chronic kidney diseaseThe diagnosis of CKD primarily focuses on the glomerular filtration rate (GFR), which assesses kidney function by measuring how well...
609
Dialysis01:27

Dialysis

2.0K
Renal failure occurs when the kidneys lose their ability to filter waste products from the blood effectively. It can be classified into two types: acute renal failure (ARF) and chronic renal failure (CRF).
Acute kidney injury develops suddenly and can be caused by pre-renal causes (e.g., hypovolemia, shock), intrinsic renal causes (e.g., acute tubular necrosis), or post-renal causes (e.g., urinary obstruction). In contrast, chronic renal failure progresses gradually over time and is often...
2.0K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Lower AKI Risk and Higher Survival With Microaxial Flow Pump Support During Elective PCI: A Propensity Score-Matched Study.

Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions·2026
Same author

Severe Pregnancy-Associated Acute Kidney Injury and Maternal Vulnerability.

Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association·2026
Same author

Pathophysiology of pregnancy-associated acute kidney injury.

Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association·2026
Same author

Extracorporeal membrane oxygenation, acute kidney injury, fluid balance, and continuous renal replacement therapy: Acute Disease Quality Initiative (ADQI) and Extracorporeal Life Support Organization (ELSO) joint consensus conference.

Intensive care medicine·2026
Same author

The global epidemiology of acute kidney injury: challenges and opportunities.

Nature reviews. Nephrology·2025
Same author

Diagnosis, diagnostic approach and challenges in pregnancy-associated AKI-the ADQI 32 consensus meeting.

Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association·2025

Related Experiment Video

Updated: Mar 28, 2026

Modeling Hypoxia/Reoxygenation Injury in Proximal Tubular Epithelial Cells
06:23

Modeling Hypoxia/Reoxygenation Injury in Proximal Tubular Epithelial Cells

Published on: November 21, 2025

660

Challenges and pitfalls when implementing renal replacement therapy in the ICU.

Ravindra L Mehta

    Critical Care (London, England)
    |January 6, 2016
    PubMed
    Summary

    Renal replacement therapy (RRT) use in the ICU varies, impacting patient outcomes. This article addresses knowledge gaps and offers a framework for optimizing RRT in critically ill patients to improve care.

    Area of Science:

    • Nephrology
    • Critical Care Medicine
    • Intensive Care Unit (ICU) Management

    Background:

    • New renal replacement therapy (RRT) methods are available for ICU patients.
    • RRT utilization in ICUs shows significant variation.
    • The need for RRT correlates with poorer patient outcomes.

    Purpose of the Study:

    • To discuss critical issues in delivering RRT to critically ill patients.
    • To provide a framework for optimal RRT application in the ICU.
    • To address knowledge gaps in RRT for ICU settings.

    Main Methods:

    • Review of current literature on RRT in critically ill patients.
    • Analysis of factors influencing RRT application in the ICU.
    • Discussion of patient and process of care elements affecting RRT.

    More Related Videos

    Surgical Techniques for Catheter Placement and 5/6 Nephrectomy in Murine Models of Peritoneal Dialysis
    07:11

    Surgical Techniques for Catheter Placement and 5/6 Nephrectomy in Murine Models of Peritoneal Dialysis

    Published on: July 19, 2018

    16.2K
    Digital Home-Monitoring of Patients after Kidney Transplantation: The MACCS Platform
    07:13

    Digital Home-Monitoring of Patients after Kidney Transplantation: The MACCS Platform

    Published on: April 12, 2021

    5.4K

    Related Experiment Videos

    Last Updated: Mar 28, 2026

    Modeling Hypoxia/Reoxygenation Injury in Proximal Tubular Epithelial Cells
    06:23

    Modeling Hypoxia/Reoxygenation Injury in Proximal Tubular Epithelial Cells

    Published on: November 21, 2025

    660
    Surgical Techniques for Catheter Placement and 5/6 Nephrectomy in Murine Models of Peritoneal Dialysis
    07:11

    Surgical Techniques for Catheter Placement and 5/6 Nephrectomy in Murine Models of Peritoneal Dialysis

    Published on: July 19, 2018

    16.2K
    Digital Home-Monitoring of Patients after Kidney Transplantation: The MACCS Platform
    07:13

    Digital Home-Monitoring of Patients after Kidney Transplantation: The MACCS Platform

    Published on: April 12, 2021

    5.4K

    Main Results:

    • RRT utilization in the ICU is inconsistent.
    • Factors influencing RRT application are complex and dynamic.
    • Knowledge gaps exist regarding optimal RRT strategies.

    Conclusions:

    • Addressing identified issues is crucial for improving RRT outcomes in ICUs.
    • A structured framework can guide the optimal use of RRT.
    • Further research is needed to refine RRT protocols for critically ill patients.