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Updated: Mar 28, 2026

Rapid Identification of Chemical Genetic Interactions in Saccharomyces cerevisiae
Published on: April 5, 2015
Use of the BioGRID Database for Analysis of Yeast Protein and Genetic Interactions
Rose Oughtred1, Andrew Chatr-aryamontri2, Bobby-Joe Breitkreutz3
1Lewis-Sigler Institute for Integrative Genomics, Princeton University, Princeton, New Jersey 08544;
Abstract:
The BioGRID database is an extensive repository of curated genetic and protein interactions for the budding yeast Saccharomyces cerevisiae, the fission yeast Schizosaccharomyces pombe, and the yeast Candida albicans SC5314, as well as for several other model organisms and humans. This protocol describes how to use the BioGRID website to query genetic or protein interactions for any gene of interest, how to visualize the associated interactions using an embedded interactive network viewer, and how to download data files for either selected interactions or the entire BioGRID interaction data set.
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