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Real-Time Assessment of Spinal Cord Microperfusion in a Porcine Model of Ischemia/Reperfusion
Published on: December 10, 2020
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Spinal cord ischemia is multifactorial: what is the best protocol?
Germano Melissano1, Luca Bertoglio, Daniele Mascia
1Scientific Institute H. San Raffaele, Chair of Vascular Surgery, "Vita Salute" San Raffaele University, Milan, Italy - melissano.germano@hsr.it.
The Journal of Cardiovascular Surgery
|January 6, 2016
Summary
Postoperative spinal cord ischemia remains a risk after thoracic aortic surgery. Prompt, aggressive management focusing on collateral circulation is crucial for potential recovery.
Area of Science:
- Neurosurgery
- Vascular Surgery
- Cardiology
Background:
- Spinal cord ischemia (SCI) is a significant risk after thoracic or thoracoabdominal aortic disease repair.
- Despite advances in understanding, the incidence of paraparesis or paraplegia remains substantial.
Purpose of the Study:
- To review current understanding and management strategies for spinal cord ischemia following aortic repair.
- To emphasize the importance of a multimodal approach and prompt intervention.
Main Methods:
- Review of existing literature on spinal cord ischemia prevention and treatment modalities.
- Discussion of open and endovascular repair techniques and their impact on SCI.
- Emphasis on collateral circulation and diagnostic tool advancements.
Main Results:
- No significant reduction in SCI rates observed with the routine use of endovascular techniques.
- Various treatment modalities show potential in improving spinal cord perfusion via collateral pathways.
- Early and aggressive management is key due to the potential reversibility of SCI.
Conclusions:
- A multimodal strategy is advocated for preventing and managing SCI after aortic procedures.
- Improved preoperative assessment of spinal vascular networks is essential for better surgical planning.
- Prompt intervention for SCI can improve outcomes by leveraging collateral circulation.

