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Reference Intervals for Routine Blood Tests in 468 Healthy Mongolian Children

Yandan Du, Hui Sun, Haiqiu Chen

    Clinical Laboratory
    |January 7, 2016
    PubMed

    Insights

    This study establishes blood parameter reference intervals for healthy Mongolian children aged 7-13 in Inner Mongolia. Findings highlight gender-specific variations in key blood cell counts, crucial for accurate pediatric health assessments.

    Area of Science:

    • Pediatric Hematology
    • Clinical Biochemistry
    • Mongolian Pediatrics

    Background:

    • Establishing accurate reference intervals for routine blood parameters is essential for diagnosing health conditions in children.
    • Previous research has not sufficiently detailed these intervals for specific pediatric populations, such as Mongolian children in the Inner Mongolia Daxingan region.

    Purpose of the Study:

    • To determine the normal reference ranges for routine blood parameters in healthy Mongolian children.
    • To analyze potential differences in these parameters based on gender and ethnic group within the study population.

    Main Methods:

    • Analyzed venous blood samples from 468 healthy children aged 7-13 years.
    • Utilized a Sysmex XE-5000 Automated Hematology Analyzer for comprehensive blood cell analysis.
    • Performed statistical analysis to compare results with national standards and evaluate gender-based differences.

    Main Results:

    • Established specific reference ranges for various blood parameters including White Blood Cell (WBC) count, Red Blood Cell (RBC) count, Hemoglobin (HGB), Hematocrit (HCT), Mean Corpuscular Volume (MCV), Mean Corpuscular Hemoglobin (MCH), Mean Corpuscular Hemoglobin Concentration (MCHC), and Platelet (PLT) count.
    • Observed statistically significant gender-based differences (p < 0.05) in WBC, RBC, MCV, MCH, MCHC, Monocyte percentage (MONO %), and Basophil percentage (BASO %).
    • No significant differences were found for other analyzed parameters (p > 0.05).

    Conclusions:

    • Blood parameter values in children are influenced by geographical location, nationality, and gender.
    • The study underscores the necessity of establishing gender- and age-specific reference intervals for Mongolian children to ensure accurate clinical interpretations.
    • These findings contribute to improved diagnostic accuracy and health monitoring for pediatric populations in the region.
    Abstract

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