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Published on: June 18, 2015
Patient and hospital determinants of primary percutaneous coronary intervention in England, 2003-2013
1Leeds Institute of Cardiovascular and Metabolic Medicine, University of Leeds, Leeds, UK.
Insights
Primary percutaneous coronary intervention (PPCI) for ST-elevation myocardial infarction (STEMI) use increased significantly but varied by patient factors and hospitals. Older, sicker patients and certain hospitals had lower PPCI rates, indicating a need for equitable care.
Area of Science:
- Cardiology
- Public Health
Background:
- Primary percutaneous coronary intervention (PPCI) is a crucial treatment for ST-elevation myocardial infarction (STEMI).
- Implementation of PPCI varies significantly across countries and healthcare systems.
Purpose of the Study:
- To investigate patient and hospital characteristics associated with PPCI utilization in England.
- To identify factors influencing the variation in PPCI rates.
Main Methods:
- Utilized national registry data (MINAP) from 84 NHS trusts in England (2003-2013).
- Employed multilevel Poisson regression to model PPCI incidence rate ratios (IRR) based on patient and trust-level factors.
Main Results:
- Standardized PPCI rates increased from 0.01% to 86.3% between 2003 and 2013.
- PPCI rates were lower for patients with comorbidities (e.g., previous MI, heart failure, diabetes, renal failure), older age, and longer travel distances.
- Higher PPCI rates were observed in trusts with more interventional cardiologists and a 24/7 PPCI service.
- Significant unexplained variation in PPCI rates existed between trusts.
Conclusions:
- Despite an 8-year implementation phase, PPCI utilization stabilized around 85%, with disparities for older and sicker patients.
- Between-trust variation in PPCI rates persisted, not fully explained by staffing levels.
- Adherence to clinical pathways for STEMI is essential to ensure equitable quality of care.
Objective:
Primary percutaneous coronary intervention (PPCI) for ST-elevation myocardial infarction (STEMI) is insufficiently implemented in many countries. We investigated patient and hospital characteristics associated with PPCI utilisation.
Methods:
Whole country registry data (MINAP, Myocardial Ischaemia National Audit Project) comprising PPCI-capable National Health Service trusts in England (84 hospital trusts; 92 350 hospitalisations; 90 489 patients), 2003-2013. Multilevel Poisson regression modelled the relationship between incidence rate ratios (IRR) of PPCI and patient and trust-level factors.
Results:
Overall, standardised rates of PPCI increased from 0.01% to 86.3% (2003-2013). While, on average, there was a yearly increase in PPCI utilisation of 30% (adjusted IRR 1.30, 95% CI 1.23 to 1.36), it varied substantially between trusts. PPCI rates were lower for patients with previous myocardial infarction (0.95, 0.93 to 0.98), heart failure (0.86, 0.81 to 0.92), angina (0.96, 0.94 to 0.98), diabetes (0.97, 0.95 to 0.99), chronic renal failure (0.89, 0.85 to 0.90), cerebrovascular disease (0.96, 0.93 to 0.99), age >80 years (0.87, 0.85 to 0.90), and travel distances >30 km (0.95, 0.93 to 0.98). PPCI rates were higher for patients with previous percutaneous coronary intervention (1.09, 1.05 to 1.12) and among trusts with >5 interventional cardiologists (1.30, 1.25 to 1.34), more visiting interventional cardiologists (1-5: 1.31, 1.26 to 1.36; ≥6: 1.42, 1.35 to 1.49), and a 24 h, 7-days-a-week PPCI service (2.69, 2.58 to 2.81). Half of the unexplained variation in PPCI rates was due to between-trust differences.
Conclusions:
Following an 8 year implementation phase, PPCI utilisation rates stabilised at 85%. However, older and sicker patients were less likely to receive PPCI and there remained between-trust variation in PPCI rates not attributable to differences in staffing levels. Compliance with clinical pathways for STEMI is needed to ensure more equitable quality of care.
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