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Updated: Mar 27, 2026

3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache
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New Daily Persistent Headache Is Most Likely to Begin at the Start of School

Leah R Grengs1, Kenneth J Mack2

  • 1Department of Neurology, Mayo Clinic, Rochester, MN, USA.

Journal of Child Neurology
|January 7, 2016
PubMed

Insights

Children are more likely to develop new daily persistent headaches at the start of the school year in September or January. This study suggests a link between school start months and headache onset in pediatric patients.

Area of Science:

  • Pediatric Neurology
  • Headache Medicine
  • Epidemiology

Background:

  • Chronic daily headaches are a significant issue in pediatric populations.
  • Understanding the onset patterns of these headaches is crucial for effective management.

Purpose of the Study:

  • To investigate if specific times of the year are associated with the onset of chronic daily headaches in children.
  • To explore potential triggers for new daily persistent headache (NDPH) and chronic migraine (CM) transitions.

Main Methods:

  • Retrospective review of medical records for 103 patients with chronic migraine and 104 patients with new daily persistent headache.
  • Analysis of patient-reported onset month for daily headaches.
  • Statistical comparison of headache onset during different months.

Main Results:

  • 39% of new daily persistent headache patients reported onset in September or January, coinciding with school start months.
  • Onset in May or June was rare for new daily persistent headaches.
  • A trend towards increased onset of chronic migraine in September and January was observed but did not reach statistical significance.

Conclusions:

  • New daily persistent headache onset is significantly higher during school start months (September and January).
  • The findings suggest a potential association between school-related factors and the initiation of daily headaches in children.
  • Further research is needed to identify the specific factors contributing to this seasonal association.

Keywords:
chronic migrainenew daily persistent headacheschool

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