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Related Experiment Video

Updated: Mar 27, 2026

3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache
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Migraine and its psychiatric comorbidities.

Mia Tova Minen1, Olivia Begasse De Dhaem2, Ashley Kroon Van Diest3

  • 1Department of Neurology, NYU Langone Medical Center, New York, New York, USA.

Journal of Neurology, Neurosurgery, and Psychiatry
|January 7, 2016
PubMed
Summary

Migraine frequently co-occurs with psychiatric conditions like depression and anxiety. Understanding these links is crucial for effective treatment of migraine and related mental health disorders.

Keywords:
MIGRAINENEUROEPIDEMIOLOGYNEUROPSYCHIATRYNEURORADIOLOGYPSYCHOPHARMACOLOGY

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Area of Science:

  • Neurology
  • Psychiatry

Background:

  • Migraine is a common neurological disorder with significant disability.
  • It frequently co-occurs with various psychiatric comorbidities, impacting patient well-being.

Purpose of the Study:

  • To review the association between migraine and psychiatric disorders.
  • To explore risk factors for migraine chronification.
  • To discuss pathophysiological links and treatment considerations.

Main Methods:

  • Literature review of existing studies.
  • Examination of data on psychiatric risk factors for migraine.
  • Discussion of neuroimaging techniques like functional brain imaging.

Main Results:

  • Migraine is widely associated with psychiatric comorbidities, including depression, anxiety, and PTSD.
  • Psychiatric factors can contribute to migraine chronification.
  • Evidence suggests shared pathophysiological mechanisms between migraine and psychiatric disorders.

Conclusions:

  • A strong link exists between migraine and numerous psychiatric comorbidities.
  • Further research is needed to clarify the underlying neurocircuitry.
  • Optimizing treatment for patients with comorbid conditions requires more investigation.