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Immunopharmacology: a new frontier.

B L Pope1

  • 1Department of Pharmacology, Dalhousie University, Halifax, N.S., Canada.

Canadian Journal of Physiology and Pharmacology
|June 1, 1989
PubMed
Summary

Immunopharmacology merges immunology and pharmacology to study chemical interactions with immune cells. This hybrid science develops new immunomodulatory drugs for clinical applications and research, expanding its role in medicine.

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Area of Science:

  • Immunopharmacology as a hybrid scientific discipline.
  • Integrates principles from immunology and pharmacology.
  • Encompasses both basic and applied research areas.

Background:

  • Basic research investigates chemical interactions with immune system cells.
  • Includes studies on lymphokines, cytokines, complement, and neuropeptides.
  • Applied research focuses on developing novel immunomodulatory drugs.

Purpose of the Study:

  • To explore the foundational mechanisms of immunopharmacology.
  • To highlight the reciprocal contributions of immunology and pharmacology.
  • To project the future growth of immunopharmacology in clinical and research settings.

Main Methods:

  • Analyzing the effects of endogenous and synthetic chemicals on immune function.
  • Utilizing antibodies developed in immunology for chemical analysis.
  • Leveraging pharmacological data on hypersensitivity and inflammation mediators.

Main Results:

  • Demonstrates significant past contributions between immunology and pharmacology.
  • Highlights the increasing clinical use of recombinant lymphokines.
  • Identifies emerging immunomodulatory substances.

Conclusions:

  • Immunopharmacology is a rapidly evolving field with expanding clinical and research significance.
  • Future research will focus on lymphokine pharmacology and targeted drug development.
  • New drugs will be rationally designed as agonists or antagonists for immune-regulating lymphokines.

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