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Molecular basis of high viscosity in concentrated antibody solutions: Strategies for high concentration drug product

Dheeraj S Tomar1, Sandeep Kumar1, Satish K Singh1

  • 1a Biotherapeutics Pharmaceutical Sciences Research and Development, Pfizer Inc. , 700 Chesterfield Parkway West, Chesterfield , Missouri , 63017 , USA.

Mabs
|January 7, 2016
PubMed

Keywords:
Electrostaticshigh concentrationhydrophobicityintermolecular interactionsmonoclonal antibody solutionnetworksviscosity

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