Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Videos

Axis determination in insect embryos.

C Nüsslein-Volhard¹, S Roth

¹Max-Planck-Institut für Entwicklungsbiologie, Tübingen, FRG.

Ciba Foundation Symposium

|January 1, 1989

Summary

This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Mutations affecting the pattern of the larval cuticle inDrosophila melanogaster : I. Zygotic loci on the second chromosome.

Wilhelm Roux's archives of developmental biology·2017

Same author

Mutations affecting the pattern of the larval cuticle inDrosophila melanogaster : II. Zygotic loci on the third chromosome.

Wilhelm Roux's archives of developmental biology·2017

Same author

Mutations affecting the pattern of the larval cuticle inDrosophila melanogaster : III. Zygotic loci on the X-chromosome and fourth chromosome.

Wilhelm Roux's archives of developmental biology·2017

Same author

Mutations affecting pigmentation and shape of the adult zebrafish.

Development genes and evolution·2013

Same author

Unique accumulation of neuropeptides in an insect: FMRFamide-related peptides in the cockroach, Periplaneta americana.

The European journal of neuroscience·2004

Same author

The neurodevelopmental progress of infants less than 33 weeks into adolescence.

Archives of disease in childhood·2004

Same journal

Precision agriculture: spatial and temporal variability of environmental quality. General reflections.

Ciba Foundation symposium·1997

Same journal

Uncertainty in hydrogeological modelling.

Ciba Foundation symposium·1997

Same journal

Optimal mapping of site-specific multivariate soil properties.

Ciba Foundation symposium·1997

Same journal

Modelling for precision weed management.

Ciba Foundation symposium·1997

Same journal

GIS support for precision agriculture: problems and possibilities.

Ciba Foundation symposium·1997

Same journal

Spatial sampling.

Ciba Foundation symposium·1997

See all related articles

Insect pattern formation involves maternal genes establishing positional cues for embryonic axis determination. Three independent systems control the anteroposterior axis, while one system governs the dorsoventral axis.

Area of Science:

Developmental Biology
Genetics
Molecular Biology

Background:

Insect pattern formation is crucial for embryonic development.
Classical and molecular approaches have elucidated mechanisms in Drosophila oogenesis.
Positional cues establish embryonic axes.

Purpose of the Study:

To model the genetic mechanisms of axis determination in Drosophila embryos.
To differentiate between proposed models of anteroposterior axis formation.

Main Methods:

Genetics and transplantation experiments in Drosophila.
Molecular biology techniques to study gene products.
Analysis of maternal and zygotic gene interactions.

Main Results:

Related Experiment Videos

Three independent maternal gene systems define the anteroposterior axis (anterior, posterior, terminal regions).
One system governs the dorsoventral axis.
Key gene products provide spatial signals for zygotic gene activation.
Zygotic gene interactions refine the initial spatial framework.

Conclusions:

The proposed model contrasts with previous single-gradient models for anteroposterior axis determination.
Concentration-dependent mechanisms likely operate in anterior and dorsoventral patterning.
Posterior patterning relies more on inter-regional gap gene interactions than signal concentration.