Distinction of individual finger responses in somatosensory cortex using ECoG high-gamma activation mapping

This study demonstrates the feasibility of high-gamma activity mapping for localization of somatosensory finger areas in the human brain. Identification of functional brain regions is important in surgical planning, such as for resections of epileptic foci or brain tumors. The mapping procedure is done using electrocorticography (ECoG), an invasive technique in which electrical brain signals are acquired from the cortical surface. Two epilepsy patients with implanted electrode grids participated in the study. Data were collected during a vibrotactile finger stimulation paradigm and showed significant cortical activation (p <; 0.001) in the high-gamma range over the contralateral somatosensory cortex. The results are consistent with previous studies that used fMRI in test subjects without implanted electrodes. Therefore, the results suggest that localizing the cortical representations of the fingers in clinical practice using ECoG is feasible, even without the patient's active participation.