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Functional Characterization of Endogenously Expressed Human RYR1 Variants
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Spatial localization of ryanodine receptors in human cardiac cells

A Vallmitjana, C Nolla, A Herraiz-Martínez

    Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference
    |January 7, 2016
    PubMed

    Abstract:

    We present a novel image processing method to determine the location of ryanodine receptors in cardiac cells. A semi-automatic manual validation by an expert has been used in order to establish the performance of the segmentation method. The approach provides high accuracy under different experimental conditions and it is robust to common sources of noise including experimental, molecular and biological fluctuations.

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