Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Raman Spectroscopy Instrumentation: Overview01:26

Raman Spectroscopy Instrumentation: Overview

1.8K
A conventional Raman spectrophotometer includes a laser source, a sample holding system, a wavelength selector, and a detector.
The monochromatic laser source, typically using visible or near-infrared radiation, generates a highly focused beam of light. This light interacts with the molecules of the sample, scattering some of the light. Liquid and gaseous samples are usually tested in ordinary glass capillaries, while solids can be analyzed as powders packed in capillaries or as potassium...
1.8K
Raman Spectroscopy: Overview01:20

Raman Spectroscopy: Overview

2.5K
The underlying principle of Raman spectroscopy is based on the interaction between light and matter, specifically molecules' inelastic scattering of photons. When a monochromatic beam of light, typically from a laser source, interacts with a sample, most scattered light has the same frequency as the incident light. This is known as Rayleigh scattering.
However, a small fraction of the scattered light exhibits a frequency shift due to the exchange of energy between the incident photons and...
2.5K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Heterologous prime-boost immunisation with mRNA- and AdC68-based 2019-nCoV variant vaccines induces broad-spectrum immune responses in mice.

Frontiers in immunology·2023
Same author

TREM2 acts as a receptor for IL-34 to suppress acute myeloid leukemia in mice.

Blood·2023
Same author

Structural characterization and anti-lipotoxicity effects of a pectin from okra (Abelmoschus esculentus (L.) Moench).

International journal of biological macromolecules·2023
Same author

Loss of EPS8 sensitizes non-small-cell lung carcinoma to chemotherapy-induced DNA damage.

Cancer gene therapy·2023
Same author

Knockdown of MEF2D inhibits the development and progression of B-cell acute lymphoblastic leukemia.

Translational cancer research·2023
Same author

Abemaciclib drives the therapeutic differentiation of acute myeloid leukaemia stem cells.

British journal of haematology·2023

Related Experiment Video

Updated: Mar 27, 2026

Non-contact, Label-free Monitoring of Cells and Extracellular Matrix using Raman Spectroscopy
13:48

Non-contact, Label-free Monitoring of Cells and Extracellular Matrix using Raman Spectroscopy

Published on: May 29, 2012

17.7K

Real-time biochemical sensor based on Raman scattering with CMOS contact imaging.

Muyun Cao, Yuhua Li, Orly Yadid-Pecht

    Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference
    |January 7, 2016
    PubMed
    Summary

    This study introduces a low-cost biochemical sensor using Raman scattering and CMOS imaging for instant solution concentration detection. The system offers comparable results to expensive spectrometers, making it ideal for various labs.

    More Related Videos

    Direct Comparison of Hyperspectral Stimulated Raman Scattering and Coherent Anti-Stokes Raman Scattering Microscopy for Chemical Imaging
    09:46

    Direct Comparison of Hyperspectral Stimulated Raman Scattering and Coherent Anti-Stokes Raman Scattering Microscopy for Chemical Imaging

    Published on: April 28, 2022

    5.0K
    Multiplex Chemical Imaging Based on Broadband Stimulated Raman Scattering Microscopy
    09:57

    Multiplex Chemical Imaging Based on Broadband Stimulated Raman Scattering Microscopy

    Published on: July 25, 2022

    4.7K

    Related Experiment Videos

    Last Updated: Mar 27, 2026

    Non-contact, Label-free Monitoring of Cells and Extracellular Matrix using Raman Spectroscopy
    13:48

    Non-contact, Label-free Monitoring of Cells and Extracellular Matrix using Raman Spectroscopy

    Published on: May 29, 2012

    17.7K
    Direct Comparison of Hyperspectral Stimulated Raman Scattering and Coherent Anti-Stokes Raman Scattering Microscopy for Chemical Imaging
    09:46

    Direct Comparison of Hyperspectral Stimulated Raman Scattering and Coherent Anti-Stokes Raman Scattering Microscopy for Chemical Imaging

    Published on: April 28, 2022

    5.0K
    Multiplex Chemical Imaging Based on Broadband Stimulated Raman Scattering Microscopy
    09:57

    Multiplex Chemical Imaging Based on Broadband Stimulated Raman Scattering Microscopy

    Published on: July 25, 2022

    4.7K

    Area of Science:

    • Biochemistry
    • Optical Engineering
    • Sensor Technology

    Background:

    • Quantitative biochemical concentration detection is crucial in chemical, biomedical, and environmental analysis.
    • Existing methods often rely on expensive and complex instrumentation, limiting accessibility.

    Purpose of the Study:

    • To develop and present a novel biochemical sensor utilizing Raman scattering and CMOS contact imaging.
    • To enable cost-effective and instant detection of solution concentrations.

    Main Methods:

    • The sensor integrates a laser diode, optical filter, sample holder, and a commercial CMOS sensor.
    • Image processing software analyzes the Raman scattering output for quantitative measurements.

    Main Results:

    • The system achieves instant measurements with a resolution between 0.2 and 0.4 Mol.
    • Performance is comparable to high-cost commercial spectrometers.

    Conclusions:

    • The developed sensor offers a low-cost, user-friendly, and small-scale solution for biochemical concentration detection.
    • This technology has significant potential for application in diverse laboratory settings.