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Mathematical analysis of dermal absorption rate of heavy metals

Izmail Batkin, Miodrag Bolic

    Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference
    |January 7, 2016
    PubMed

    Insights

    Disposable diapers may increase children's exposure to heavy metals, potentially impacting neurodevelopment. Our mathematical model suggests significant dermal reabsorption of toxicants excreted in urine and feces.

    Area of Science:

    • Environmental Health
    • Toxicology
    • Neurodevelopmental Disorders

    Background:

    • Over 90% of US children use disposable diapers until age 30 months.
    • Diapers absorb waste containing toxicants, including heavy metals.
    • Heavy metals are statistically linked to autism and neurodevelopmental disorders.

    Purpose of the Study:

    • To investigate the potential for increased dermal reabsorption of toxicants from disposable diapers.
    • To quantify the impact of diaper use on body toxicant levels.

    Main Methods:

    • Development of a mathematical kinetic model.
    • Analysis of toxicant reabsorption through the skin.

    Main Results:

    • The model indicates an average toxicant reabsorption factor between 1.6 and 5.
    • This suggests a significant increase in body toxicant levels due to dermal absorption.

    Conclusions:

    • Disposable diapers may contribute to increased body burden of heavy metals in children.
    • Further experimental verification is needed to confirm these mathematical findings.

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